基本信息
浏览量:0
职业迁徙
个人简介
Description of Research Expertise
Research area:
The pathogenesis of cancer involves not only intrinsic genetic alterations in tumor cells but also the failure of immune surveillance and unresolved inflammation. However, it is not well understood how host-intrinsic or environmental factors direct the immune response towards tumor-promoting inflammation versus anti-tumor immunity during tumor progression. In particular, mucosal surfaces exposed to the external environment are colonized by a vast number of microbes, collectively referred to as the commensal microbiota. Our work and the work of others have just begun to unveil the critical role of commensal microbiome in shaping the tumor microenvironment (TME) at the mucosal sites to regulate the tumor-immune interactions. This is as an area of tremendous opportunity for significant breakthroughs in cancer research.
Research area:
The pathogenesis of cancer involves not only intrinsic genetic alterations in tumor cells but also the failure of immune surveillance and unresolved inflammation. However, it is not well understood how host-intrinsic or environmental factors direct the immune response towards tumor-promoting inflammation versus anti-tumor immunity during tumor progression. In particular, mucosal surfaces exposed to the external environment are colonized by a vast number of microbes, collectively referred to as the commensal microbiota. Our work and the work of others have just begun to unveil the critical role of commensal microbiome in shaping the tumor microenvironment (TME) at the mucosal sites to regulate the tumor-immune interactions. This is as an area of tremendous opportunity for significant breakthroughs in cancer research.
研究兴趣
论文共 31 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn