基本信息
浏览量:3
职业迁徙
个人简介
In 2008, we found T cell antigen receptor (TCR) phosphorylation is regulated via the dynamic interaction between TCR intracellular tyrosine motifs and plasma membrane (Xu et al, 2008). This work unveils the presence of an unexpected plasma membrane regulation to immunoreceptor activation other than the well-studied kinase-phosphatase regulation. In addition to study immunoreceptor activation mechanism, we are currently utilizing functional and structural approaches to identify and characterize new signaling proteins involved in immunoreceptor signaling and their roles in human cancers. These studies will advance our knowledge about T cell signaling as well as identify potential drug targets for treating human cancers.
研究兴趣
论文共 94 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
National Science Open (2024)
Yibing Bai,Tongzhou Li, Qinshu Wang,Weiqiang You, Haochen Yang,Xintian Xu,Ziyi Li,Yu Zhang,Chengsong Yan,Lei Yang,Jiaqian Qiu,Yuanhua Liu,
EMBO Molecular Medicineno. 2 (2024): 334-360
Life Metabolismno. 5 (2023)
Jian Chen,Shizhen Qiu,Wentao Li,Kun Wang,Yu Zhang,Han Yang, Baichuan Liu,Guangfei Li,Li Li,Min Chen, Junjie Lan,Jiahua Niu,
Hui Chen,Xinyi Xu,Wei Hu,Songfang Wu, Jianhui Xiao,Peng Wu, Xiaowen Wang,Xuling Han,Yanruo Zhang,Yong Zhang,Ning Jiang,Wanli Liu,
Proceedings of the National Academy of Sciences of the United States of Americano. 28 (2023)
引用0浏览0WOS引用
0
0
Journal of medical virologyno. 2 (2023)
Blood (2023)
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn