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个人简介
The research interest of Dr. Chu’s laboratory is dendritic cell (DC) biology. There are two major topics for studying the function and regulation of DCs in immune system in this laboratory:
1. Endogenous factors of DCs
These basic researches are the topics in biomedical sciences. We study the role of DCs in immune system by using various transgenic and knock-out mice, such as deficiency of Src or Syk kinase. We also use these mice as disease models to study the pathogenesis.
2. Exogenous factors of DCs
These applied researches are the topics in biotechnology. We study the functions of DCs in immune system by screening various immunomodulators from foods, herbs, and chemicals. We also ask some basic questions in chemical biology.
Our goal is to apply the information from the studies of both endogenous and exogenous factors into translational medicine. We hope to develop efficient strategies, such as vaccines and immunotherapies, to treat inflammation, autoimmune diseases and cancers.
1. Endogenous factors of DCs
These basic researches are the topics in biomedical sciences. We study the role of DCs in immune system by using various transgenic and knock-out mice, such as deficiency of Src or Syk kinase. We also use these mice as disease models to study the pathogenesis.
2. Exogenous factors of DCs
These applied researches are the topics in biotechnology. We study the functions of DCs in immune system by screening various immunomodulators from foods, herbs, and chemicals. We also ask some basic questions in chemical biology.
Our goal is to apply the information from the studies of both endogenous and exogenous factors into translational medicine. We hope to develop efficient strategies, such as vaccines and immunotherapies, to treat inflammation, autoimmune diseases and cancers.
研究兴趣
论文共 75 篇作者统计合作学者相似作者
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I-Tsu Chyuan,Hsiu-Jung Liao,Tse-Hua Tan, Huai-Chia Chuang, Yu-Chuan Chu, Meng-Hsun Pan,Chien-Sheng Wu,Ching-Liang Chu, Bor-Ching Sheu,Ping-Ning Hsu
Journal of Biomedical Scienceno. 1 (2024): 1-16
Po-Yan Hsiao,Ren-Yeong Huang, Lin-Wei Huang,Ching-Liang Chu, Thomas Van Dyke, Lian-Ping Mau,Chia-Dan Cheng,Cheng-En Sung,Pei-Wei Weng,Yu-Chiao Wu,Yi-Shing Shieh,Wan-Chien Cheng
JOURNAL OF PERIODONTOLOGY (2024)
Po‐Yan Hsiao,Ren‐Yeong Huang, Lin‐Wei Huang,Ching‐Liang Chu,Thomas Van Dyke, Lian‐Ping Mau,Chia‐Dan Cheng, Cheng‐En Sung,Pei‐Wei Weng,Yu‐Chiao Wu,Yi‐Shing Shieh, Wan‐Chien Cheng
Journal of Periodontology (2024)
Ju-Pi Li,Ching-Liang Chu,Wan-Ru Chao, Cheng-Siang Yeh,Yi-Ju Lee,Dz-Chi Chen,Shun-Fa Yang,Yu-Hua Chao
Agingno. 9 (2023): 3621-3634
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