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Much of our ongoing research during the past 30 years addresses two issues:
Oxidative modification of lipids in membranes and in plasma lipoproteins, dependence of the oxidation resistance of lipids on various factors, including physiological and pathological conditions, including lipid dislipodemiaand antioxidants and basic aspects of the mechanics involved in lipid oxidation, using both lipoproteins and liposomalmodel systems.
Solubilization of lipids, phospholipids and membranes by detergents. These processes are of significance with respect to solubilizationand reconstitution of biological membranceas well as in the naturally-occurring solubilization of dietary lipids (including cholesterol). Our studies address mechanistic, thermodynamic and structural aspects of these processes.
Much of our ongoing research during the past 30 years addresses two issues:
Oxidative modification of lipids in membranes and in plasma lipoproteins, dependence of the oxidation resistance of lipids on various factors, including physiological and pathological conditions, including lipid dislipodemiaand antioxidants and basic aspects of the mechanics involved in lipid oxidation, using both lipoproteins and liposomalmodel systems.
Solubilization of lipids, phospholipids and membranes by detergents. These processes are of significance with respect to solubilizationand reconstitution of biological membranceas well as in the naturally-occurring solubilization of dietary lipids (including cholesterol). Our studies address mechanistic, thermodynamic and structural aspects of these processes.
研究兴趣
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Antioxidants (Basel, Switzerland)no. 6 (2023): 1188-1188
mag(2017)
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