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At about the same time, he became involved in the Minnesota Heart Health Program (MHHP), serving initially as Co-Youth Education Director with Cheryl Perry, then as Associate Health Program Director with Maury Mittelmark, and later as Health Program Director and Co-Principal Investigator with Henry Blackburn, Russell Luepker, David Jacobs, Neil Bracht, and the other MHHP investigators. At the time, the MHHP was the largest NIH grant ever awarded to the University of Minnesota. It was one of three community-based heart disease prevention programs funded by the NHLBI in the 1980s and early 1990s, and helped create the basis for the community-based health promotion and disease prevention programs we see today.
Many other studies developed out of the MHHP, including the Promotion of Healthy Eating Patterns in Youth (Cheryl Perry, PI), Children’s Activity Trial for Cardiovascular Health (Cheryl Perry, PI), and Models for Treating High Blood Cholesterol (Russell Luepker, PI). All were funded by the NHLBI.
Most of these studies were examples of group-randomized trials. In these studies, identifiable social groups are the unit of assignment, while members of those groups are the units of observations. The design and analytic issues inherent in these studies were not well understood in the 1980s and 1990s, though Jerome Cornfield’s classic paper, Randomization by Group: A Formal Analysis, was published in 1978. Dr. Murray became increasingly interested in these issues, collaborating with Peter Hannan and others at Minnesota, and learning from pioneers in this area, including Allan Donner.
Dr. Murray’s first interaction with the ODP occurred in 1992, when the Office sponsored a meeting of methodologists from survey research, educational statistics, biostatistics, and epidemiology for the first NIH conference on the design and analysis of group-randomized trials. Dr. Murray coordinated that meeting, which was convened under the auspices of Dr. William Harlan, the third Associate Director for Prevention and Director of the ODP.
Many other studies developed out of the MHHP, including the Promotion of Healthy Eating Patterns in Youth (Cheryl Perry, PI), Children’s Activity Trial for Cardiovascular Health (Cheryl Perry, PI), and Models for Treating High Blood Cholesterol (Russell Luepker, PI). All were funded by the NHLBI.
Most of these studies were examples of group-randomized trials. In these studies, identifiable social groups are the unit of assignment, while members of those groups are the units of observations. The design and analytic issues inherent in these studies were not well understood in the 1980s and 1990s, though Jerome Cornfield’s classic paper, Randomization by Group: A Formal Analysis, was published in 1978. Dr. Murray became increasingly interested in these issues, collaborating with Peter Hannan and others at Minnesota, and learning from pioneers in this area, including Allan Donner.
Dr. Murray’s first interaction with the ODP occurred in 1992, when the Office sponsored a meeting of methodologists from survey research, educational statistics, biostatistics, and epidemiology for the first NIH conference on the design and analysis of group-randomized trials. Dr. Murray coordinated that meeting, which was convened under the auspices of Dr. William Harlan, the third Associate Director for Prevention and Director of the ODP.
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Ethnicity & Diseaseno. Special Issue (2023): 1-5
TRIALSno. 1 (2022): 987-12
June Stevens,David M. Murray,Chris D. Baggett,John P. Elder,G. Timothy, Lohman,Leslie A. Lytle,Russell R. Pate,Charlotte A. Pratt,Margarita S. Treuth, Larry,S. Webber,
semanticscholar(2019)
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