基本信息
浏览量:176
职业迁徙
个人简介
David Adelson is Professor and Chair of Bioinformatics and Computational Genetics, Zhendong Chair of Molecular Traditional Chinese Medicine in the School of Biological Sciences at the University of Adelaide and is also a Xinglin Scholar Professor at Guangzhou University of TCM. Prof. Adelson’s current research also focuses on the non-coding portions of animal genomes, such as regions used to transcribe ncRNAs (piRNAs and lncRNAs) and the computational analysis of repetitive, so called “Junk DNA”, in order to understand large scale evolutionary/structural changes in animal genomes. Prof. Adelson has led the analysis of repetitive DNA for the cow, horse and elephant genome sequencing consortia and his lab has recently finished working on the Tuatara repetitive DNA analysis for that international genome sequencing consortium. In addition to characterising repeat content in genomes, his lab continues to develop a set of tools to identify and annotate transposable elements and segmental duplications “from scratch” and to use long read sequencing technology to identify somatic structural variants.. Additional aspects of the genome evolution work include understanding the impact of horizontal transfer of repetitive elements in higher organisms.
Prof. Adelson is currently Director of the Zhendong Centre of Molecular Traditional Chinese Medicine. The philosophy of the Zhendong Centre is that complex molecular effects of TCM preparations will provide a molecular basis for understanding the mode of action of TCM and support integration into Western medicine. A major approach to this work uses transcriptome analysis to identify entire pathways or co-expression sub-networks in cancer cells that are altered as a result of a particular TCM preparation, Compound Kushen Injection.
Prof. Adelson is also Co-Director (with Prof Gary Glonek) of the Bioinformatics Hub, a core facility for bioinformatics training and analysis that serves the research community of The University of Adelaide.
Research:
1)understanding how transposable elements affect genome structure and function at both the individual and species level and 2)using systems biology and network based methods to understand the molecular mode of action of complex mixtures of bioactives such as Traditional Chinese Medicines.
Prof. Adelson is currently Director of the Zhendong Centre of Molecular Traditional Chinese Medicine. The philosophy of the Zhendong Centre is that complex molecular effects of TCM preparations will provide a molecular basis for understanding the mode of action of TCM and support integration into Western medicine. A major approach to this work uses transcriptome analysis to identify entire pathways or co-expression sub-networks in cancer cells that are altered as a result of a particular TCM preparation, Compound Kushen Injection.
Prof. Adelson is also Co-Director (with Prof Gary Glonek) of the Bioinformatics Hub, a core facility for bioinformatics training and analysis that serves the research community of The University of Adelaide.
Research:
1)understanding how transposable elements affect genome structure and function at both the individual and species level and 2)using systems biology and network based methods to understand the molecular mode of action of complex mixtures of bioactives such as Traditional Chinese Medicines.
研究兴趣
论文共 178 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Jingjing Cai, Yongdi Zhang,Reqing He,Liyun Jiang,Zhipeng Qu,Jinbao Gu,Jun Yang, María Florencia Legascue,Zhen-Yu Wang,Federico Ariel,David L Adelson,Youlin Zhu,
EMBO reportsno. 2 (2024): 796-812
PLoS computational biologyno. 2 (2024): e1011868-e1011868
Mobile DNAno. 1 (2024): 1-8
biorxiv(2024)
Developmental cellno. 13 (2023): 1206-1217.e4
引用1浏览0WOS引用
1
0
Denghao Wu,James Zuiani,Christopher Drogemuller,Sunita De Sousa,David Adelson,David J. Torpy, Patrick Toby H. Coates
TRANSPLANTATIONno. 10 (2023): 140-140
引用0浏览0引用
0
0
Molecular plantno. 8 (2023): 1339-1353
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn