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My research is focused on the role of non-coding RNA transcription in cancer as it relates to tumorigenesis and as novel biomarkers. I have recently published the finding that satellite RNA transcription is aberrantly expressed at high levels in pancreatic cancer compared to normal pancreas. The role of these satellite transcripts in cancer development are not fully understood and is an active area of interest in my research. In addition, the HSATII satellite is exquisitely specific for pancreatic cancer and this biomarker is present in pre-neoplastic pancreatic lesions. Given this, it is a promising novel biomarker for early detection and merits further investigation as a clinical diagnostic. In addition, our laboratory has developed microfluidic technology capable of capturing capture circulating tumor cells (CTCs) in the peripheral blood of cancer patients. Using non-coding satellite RNA as a biomarker with the CTCs may be used for an effective non-invasive early detection diagnostic.
研究兴趣
论文共 296 篇作者统计合作学者相似作者
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Cancer Letters (2024): 216713-216713
Marc Wehrli,Samantha Guinn,Filippo Birocchi, Adam Kuo,Yi Sun,Rebecca C Larson, Antonio J Almazan,Irene Scarfò,Amanda A Bouffard,Stefanie R Bailey, Praju Vikas Anekal, Paula Montero Lopis,
Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Izabella Zamora, Milan Parikh, Bidish K. Patel,Lynn Bi, Doron Haviv, Jingyi Cao,Carina Shiau, Martin Hemberg,William L. Hwang,Nir Hacohen,David T. Ting,Arnav Mehta
Cancer Researchno. 6_Supplement (2024): 3873-3873
Elad Horwitz,Taronish Dorab Dubash, Anna Szabolcs,Ben S. Wittner,Johannes Kreuzer,Robert Morris,Aditya Bardia,Brian Chirn,Devon Wiley,Dante Che, Hunter C. Russel, Xcanda I. Herrera Lopez,
biorxiv(2024)
Eunae You, Bidish Patel, Alexandra Rojas, Natalie Ho, Siyu Sun, Michael Raabe, Yuhui Song, Ildiko Phillips,Katherine Xu, Peter Richieri,Linda Nieman, Benjamin Greenbaum,
Cancer Researchno. 6_Supplement (2024): 7480-7480
Shahrzad Arya, Seyed Amir Sanatkar,Marco Ventin,Giulia Cattaneo, Cristina Martin,Gabriella Lionetto,Jingyu Jia, Feng Chen,David T. Ting,Xinhui Wang,Sandra Ryeom,Cristina R. Ferrone,
Cancer Researchno. 6_Supplement (2024): 6313-6313
Cancer Researchno. 6_Supplement (2024): 5675-5675
Milan Parikh,Ryan Park,Aparna R. Parikh, Julie L. Koenig, Leon Pappas,Moshe Sade-Feldman,Lynn Bi,Nicole Carzo, Tarin M. Grillo,Islam Baiev, Olanike Asupoto,Irena Gushterova,
Cancer Researchno. 6_Supplement (2024): 1194-1194
Carina Shiau, Jingyi Cao,Mark T. Gregory, Dennis Gong,Xunqin Yin,Jae-Won Cho,Peter L. Wang,Jennifer Su,Steven Wang,Jason W. Reeves,Tae Kyung Kim,Youngmi Kim,
bioRxiv : the preprint server for biology (2023)
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David T. Miyamoto,Richard J. Lee,Mark Kalinich, Joseph A. LiCausi,Yu Zheng,Tianqi Chen,John D. Milner,Erin Emmons,Uyen Ho, Katherine Broderick,Erin Silva,Sarah Javaid,
crossref(2023)
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