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The Speicher laboratory is a recognized leader in the field of proteomics, the systematic study of the full set of proteins produced by a given cell, tissue, or organism. Using state-of-the-art proteomics and associated computational methods, many of which were developed or optimized in the Speicher laboratory, this research group is investigating protein changes associated with a number of different cancers, innate resistance to viral infection, red cell diseases, ectopic pregnancy and other clinical disorders. The laboratory is also using structural mass spectrometry techniques coupled with molecular modeling to determine medium resolution structures of large protein complexes and characterize conformational changes involved with physiological processes.
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论文共 253 篇作者统计合作学者相似作者
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Jayaraju Dheekollu,Andreas Wiedmer,Samantha S Soldan, Leonardo Josué Castro-Muñoz, Christopher Chen,Hsin-Yao Tang,David W Speicher,Paul M Lieberman
PLoS pathogensno. 6 (2023): e1010478-e1010478
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bioRxiv : the preprint server for biology (2023)
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Kurt T. Barnhart,Kassie Jean Bollig,Suneeta Senapati, Jared Robins,Peter Takacs,Daniel Haisenleder,David W. Speicher,Nathanael C. Koelper
FERTILITY AND STERILITYno. 4 (2023): e234-E234
Jae Ho Seo,Ekta Agarwal,Kelly G. Bryant,M. Cecilia Caino,Eui Tae Kim, Andrew V. Kossenkov, Hsin-Yao Tang,Lucia R. Languino,Dmitry I. Gabrilovich,Andrew R. Cohen,David W. Speicher,Dario C. Altieri
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Journal of Biological Chemistryno. 6 (2023): 104774-104774
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Xue Hao,Bo Zhao, Martina Towers,Liping Liao, Hsin Yao Tang,Aaron Havas,Andrew V. Kossenkov,Shelley Berger,Peter D. Adams,David W. Speicher,Rugang Zhang
CANCER RESEARCHno. 2 (2023)
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