Di Zhao

Center for Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Mailbox 210, #24 Tongjiaxiang, Nanjing, Jiangsu 210009, People’s Republic of China

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Papers65 papers

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Pharmacokinetics, tissue distribution and excretion study of Oroxylin A, Oroxylin A 7-O-glucuronide and Oroxylin A sodium sulfonate in rats after administration of Oroxylin A

Guanghui Ren, Huili Chen,Mei Zhang, Nan Yang, Hui Yang, Chuanru Xu, Jiaming Li, Chen Ning, Zhongjin Song, Shiyu Zhou, Yueying Bian,Yang Lu

Fitoterapia, (2020): 104480

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Improved pharmacokinetic characteristics of ursolic acid in rats following intratracheal instillation and nose-only inhalation exposure

Chang Ren, Dexuan Kong,Chen Ning, Han Xing, Yujie Cheng,Yongjie Zhang,Yang Lu,Ning Li,Xijing Chen,Di Zhao

Journal of pharmaceutical sciences, (2020)

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A rapid HPLC-MS/MS method for determining busulfan in hemolysis samples from children with hematopoietic stem cell transplantation

Yuan Jinjie, Ning Sun, Shuyu Zhang, Xinying Feng,Xijing Chen,Di Zhao,Libo Zhao

BIOMEDICAL CHROMATOGRAPHY, no. 9.0 (2020)

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Influences of ABC transporter and CYP3A4/5 genetic polymorphisms on the pharmacokinetics of lenvatinib in Chinese healthy subjects

Jiaming Li, Xiaoqian Wang, Chen Ning, Zhaoyu Wang, Yao Wang, Ming Zheng, Siliang Zhang,Yang Lu, Yongjie Zhang,Ning Li,Xijing Chen,Di Zhao

European journal of clinical pharmacology, (2020)

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A systematic metabolic pathway identification of Common Gardenia Fruit (Gardeniae Fructus) in mouse bile, plasma, urine and feces by HPLC-Q-TOF-MS/MS

Jing Zhou, Yongjie Zhang,Ning Li,Di Zhao,Yang Lu, Lirui Wang,Xijing Chen

Journal of Chromatography B, (2020): 122100

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Interactions between Oroxylin A with the solute carrier transporters and ATP-binding cassette transporters: Drug transporters profile for this flavonoid

Guanghui Ren, Zhiying Qin, Nan Yang, Huili Chen, Kejia Fu, Chengcan Lu,Yang Lu,Ning Li, Yongjie Zhang,Xijing Chen,Di Zhao

Chemico-Biological Interactions, (2020): 109097

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Determination of Oroxylin A, Oroxylin A 7-O-glucuronide, and Oroxylin A sodium sulfonate in beagle dogs via ultra-high-performance liquid chromatography/tandem mass spectrometry: Application in a pharmacokinetic study

Guanghui Ren, Huili Chen,Mei Zhang, Nan Yang, Hui Yang, Chuanru Xu, Jiaming Li, Chen Ning, Zhongjin Song, Shiyu Zhou, Siliang Zhang, Xiaoqian Wang

Journal of separation science, (2020)

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A systematic metabolic pathway identification of Common Gardenia Fruit (Gardeniae Fructus) in mouse bile, plasma, urine and feces by HPLC-Q-TOF-MS/MS

Jing Zhou,Yongjie Zhang,Ning Li,Di Zhao,Yang Lu, Lirui Wang,Xijing Chen

Journal of Chromatography A, (2020)

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Oroxylin A, a methylated metabolite of baicalein, exhibits a stronger inhibitory effect than baicalein on the CYP1B1-mediated carcinogenic estradiol metabolite formation: Oroxylin A has a stronger inhibition than baicalein for CYP1B1

Dongchen An, Zhongjin Song, Yingyue Yi,Qing Zhang, Jinfeng Liu,Yongjie Zhang, Jing Zhou, Guanghui Zhao, Danhua Cong,Ning Li,Yang Lu,Xijing Chen

Phytotherapy Research, (2019)

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Simultaneous determination of deuterated vortioxetine and its major metabolite in human plasma by UPLC-MS/MS and application to a pharmacokinetic study in healthy volunteers

Yingyue Yi, Guanghui Ren, Ming Zheng,Di Zhao,Ning Li, Xijng Chen,Yang Lu

Journal of Chromatography B, (2019): 121955

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Pulmonary delivery alters the disposition of raloxifene in rats

Ying Kong, Hui Cai, Han Xing, Chang Ren, Dexuan Kong, Chen Ning,Ning Li,Di Zhao,Xijing Chen,Yang Lu

The Journal of pharmacy and pharmacology, (2019)

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ABCC2 c.-24 C>T single-nucleotide polymorphism was associated with the pharmacokinetic variability of deferasirox in Chinese subjects

Kangna Cao, Guanghui Ren, Chengcan Lu, Yao Wang, Yanan Tan, Jing Zhou, Yongjie Zhang,Yang Lu,Ning Li,Xijing Chen,Di Zhao

European Journal of Clinical Pharmacology, no. 1 (2019): 51-59

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Permeability and transport mechanism of trihexyphenidyl hydrochloride in Caco-2 cell monolayer model with a validated UPLC-MS/MS method

Chengcan Lu, Kejia Fu, Kangna Cao, Jiali Wei, Jing Zhou,Di Zhao,Ning Li,Yang Lu,Xijing Chen, Yongjie Zhang

Journal of Pharmaceutical and Biomedical Analysis, (2019): 112924

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PEG-conjugated triacontanol micelles as docetaxel delivery systems for enhanced anti-cancer efficacy

Xiaoyu Lu, Min Fang, Yue Yang, Yu Dai, Jiaqiu Xu,Di Zhao,Yang Lu,Xijing Chen, Shan Lu,Ning Li

Drug Delivery and Translational Research, no. 1 (2019): 122-135

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Systemic Evaluation on the Pharmacokinetics of Platinum-Based Anticancer Drugs From Animal to Cell Level: Based on Total Platinum and Intact Drugs

Zhiying Qin, Guanghui Ren, Jinjie Yuan, Huili Chen,Yang Lu,Ning Li, Yongjie Zhang,Xijing Chen,Di Zhao

Frontiers in pharmacology, (2019): 1485

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Formulation and characterization of spray-dried powders containing vincristine-liposomes for pulmonary delivery and its pharmacokinetic evaluation from in vitro and in vivo

Jiaqiu Xu, Xiaoyu Lu,Xiaojie Zhu, Yue Yang,Qi Liu,Di Zhao,Yang Lu, Jiayu Wen,Xijing Chen,Ning Li

Journal of Pharmaceutical Sciences, no. 10 (2019): 3348-3358

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Effects of the ABCB1 and ABCG2 polymorphisms on the pharmacokinetics of afatinib in healthy Chinese volunteers

Yanan Tan, Kangna Cao, Guanghui Ren, Zhiying Qin,Di Zhao,Ning Li,Xijing Chen, Yufeng Xia,Yang Lu

Xenobiotica; the fate of foreign compounds in biological systems, pp.1-21, (2019)

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An Investigation on Glucuronidation Metabolite Identification, Isozyme Contribution, and Species Differences of GL-V9 In Vitro and In Vivo

Han Xing, Dexuan Kong,Chen Ning, Ying Kong, Chang Ren, Yujie Cheng, Hui Cai,Jubo Wang,Di Zhao,Ning Li,Xijing Chen,Zhiyu Li

Molecules (Basel, Switzerland), no. 8 (2019): 1576

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Determination of GL-V9, a derivative of wogonin, in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study after oral and pulmonary administration

Han Xing, Chang Ren, Ying Kong, Qi Ni, Zeyu Wang,Di Zhao,Ning Li,Xijing Chen,Yang Lu

BIOMEDICAL CHROMATOGRAPHY, no. 8.0 (2019)

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Mechanistic study of absorption and first-pass metabolism of GL-V9, a derivative of wogonin

Han Xing, Chang Ren, Ying Kong,Chen Ning, Dexuan Kong,Yongjie Zhang,Di Zhao,Ning Li, Zeyu Wang,Xijing Chen,Yang Lu

BIOPHARMACEUTICS & DRUG DISPOSITION, no. 3-4 (2019): 151.0-161

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Papers65 papers

Di Zhao