I have since 1986 been involved in basic research and clinical trials ranging from chemoprevention of lung cancer to treatment of advanced disease (non) small cell lung cancer. I have been principle investigator of several national and international phase II and III trials.

In the last decade the focus of my research has been on translational oncology and molecular imaging. These research activities resulted in over 300 publications in peer reviewed journals and chapters in books.

I am also active in several national and international societies such as IASLC, EORTC, ASCO and AACR. I served as a chair of multidisciplinairy task force for development of clinical guidelines in small cell lung cancer in The Netherlands.

Since 2011 I have been member of the ESMO Lung and other thoracic tumours Faculty Group.

I am on the review board of several major oncology journals and co-organised several national meetings on thoracic oncology and (post) graduate teaching courses. I have been involved as a promotor and co-reader of over 20 PhD students in The Netherlands.