Dr Letellier is PI in the Molecular Disease Mechanisms group at the University of Luxembourg. Since joining the University in 2009, she works on colorectal cancer and its tumour environment. She is particularly interested in deciphering the role of microenvironmental stimuli, such as hypoxia, but also cyokines emerging from stromal-associated fibroblasts (CAFs), on tumour cells. Ultimately, her current projects aim at understanding how tumour initiation occurs and how tumour cells can disseminate and form clinical relevant macrometastases at a secondary organ.