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Biocatalytic synthesis of bio-based materials and chemicals
Plants sustainably synthesize the most abundant and among the most diverse biopolymers and biochemicals on Earth. By applying recent advances in life sciences (e.g. genomics, high-throughput functional screens, protein design), we are developing microbial enzymes and non-catalytic proteins that fine-tune the chemical, physical and morphological properties of main plant fibre components, namely cellulose, hemicelluloses, and lignins. In this way, our aim is to focus the exquisite selectivity of biocatalysts on upgrading renewable biopolymers for broader use in resource-efficient and high-value material applications. Our approach to developing high-value products from renewable bioresources benefits from three key advantages of biocatalytic reactions, 1) high specificity that is critical to controlled modification of complex starting materials, 2) mild reaction requirements that retain valuable properties of starting plant materials (e.g. degree of polymerization), and 3) ready “programmability” of biocatalysts through protein engineering, to optimize reaction efficiency and specificity.
The biotechnologies and bio-based products developed through our research supports the establishment of circular bio-based economies that reduce our reliance on fossil fuels while creating new opportunities for forest and agricultural sectors that support many small communities across our country.
Biocatalytic synthesis of bio-based materials and chemicals
Plants sustainably synthesize the most abundant and among the most diverse biopolymers and biochemicals on Earth. By applying recent advances in life sciences (e.g. genomics, high-throughput functional screens, protein design), we are developing microbial enzymes and non-catalytic proteins that fine-tune the chemical, physical and morphological properties of main plant fibre components, namely cellulose, hemicelluloses, and lignins. In this way, our aim is to focus the exquisite selectivity of biocatalysts on upgrading renewable biopolymers for broader use in resource-efficient and high-value material applications. Our approach to developing high-value products from renewable bioresources benefits from three key advantages of biocatalytic reactions, 1) high specificity that is critical to controlled modification of complex starting materials, 2) mild reaction requirements that retain valuable properties of starting plant materials (e.g. degree of polymerization), and 3) ready “programmability” of biocatalysts through protein engineering, to optimize reaction efficiency and specificity.
The biotechnologies and bio-based products developed through our research supports the establishment of circular bio-based economies that reduce our reliance on fossil fuels while creating new opportunities for forest and agricultural sectors that support many small communities across our country.
研究兴趣
论文共 139 篇作者统计合作学者相似作者
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Celluloseno. 1 (2024): 147-168
Hongbo Zhao,Johanna Karppi, Owen Mototsune, Daria Poshina, Jenny Svartström, Thi Truc Minh Nguyen, Tri Minh Vo,Adrian Tsang,Emma Master,Maija Tenkanen
Biotechnology for Biofuels and Bioproductsno. 1 (2024): 1-22
Majid Haddad Momeni,Aleksi Zitting, Vilma Jäämuru, Rosaliina Turunen,Paavo Penttilä, Garry W. Buchko, Salla Hiltunen,Natalia Maiorova,Anu Koivula,Janak Sapkota,Kaisa Marjamaa,Emma R. Master
Biotechnology for Biofuels and Bioproductsno. 1 (2024): 1-16
Biotechnology for Biofuels and Bioproductsno. 1 (2024): 34-34
ACS SUSTAINABLE CHEMISTRY & ENGINEERINGno. 4 (2023): 1294-1304
Biotechnology for biofuels and bioproductsno. 1 (2023): 132-14
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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CELLULOSEno. 17 (2023): 10783-10794
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Deepika Dahiya,Taru Koitto, Kim Kutvonen,Yan Wang, Majid Haddad Momeni, Siiri de Ruijter,Emma R Master
Bioresource technology (2023): 130188-130188
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