基本信息
views: 6
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
I have a broad background in protein/peptide chemistry, microbiology, and immunology, with specific training and expertise in the structure and function of membrane-tethered mucins, particularly MUC1, in epithelial biology. As a predoctoral student at Wayne State University School of Medicine, I purified and characterized the β2-microglobulin subunit of the major histocompatibility complex (MHC) class I molecules that are responsible for host immune recognition of microbial pathogens. As a postdoctoral fellow at the NIH, I continued this line of research, defining the structure-function relationship of mouse MHC class I proteins. As a member of the faculty at George Washington University School of Medicine and the University of Maryland School of Medicine, I continued studies of host-pathogen interactions at mucosal surfaces, receiving a Dalsemer Award from the American Lung Association to pursue these investigations. I discovered that MUC1 is an airway epithelial cell surface receptor for Pseudomonas aeruginosa and provided the first credible evidence at the molecular level of this host-pathogen interaction that is becoming the paradigm for ligand-receptor studies in airway epithelial cell biology.
Research Interests
Papers共 227 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Ethel Apolinario,James Sinclair,Myeongjin Choi, Kun Luo,Surekha Shridhar,Sharon M Tennant,Raphael Simon,Erik Lillehoj,Alan Cross
Journal of immunological methods (2024): 113701-113701
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn