基本信息
浏览量:330
职业迁徙
个人简介
Evanthia Galanis, M.D., has a long-standing interest in developing novel therapeutic approaches for cancer treatment. The focus of her laboratory is to develop and optimize novel virotherapy approaches with special emphasis on paramyxoviruses. A number of different strategies are tested, including use of therapeutic transgenes; trackable markers; combinations with small molecules, cytotoxic agents and radiation therapy; re-targeting of viral strains against tumor-specific antigens; development of novel viral delivery approaches; and exploration of immunomodulatory methods to modify humoral and innate immunity as a means of optimizing virotherapy efficacy.
A significant impetus for Dr. Galanis' research has been the translation of laboratory advances into clinical trials of novel virotherapeutics and small molecules in cancer patients. She has served as the principal investigator in multiple phase I and II virotherapy trials in different solid tumors (ovarian cancer, glioblastoma, renal cell carcinoma, colorectal cancer, melanoma, hepatocellular carcinoma), and she has spearheaded the clinical translation of measles derivatives and their first human testing in patients with ovarian cancer or brain tumors, as well as first human use of live cell carriers for oncolytic virus delivery.
A significant impetus for Dr. Galanis' research has been the translation of laboratory advances into clinical trials of novel virotherapeutics and small molecules in cancer patients. She has served as the principal investigator in multiple phase I and II virotherapy trials in different solid tumors (ovarian cancer, glioblastoma, renal cell carcinoma, colorectal cancer, melanoma, hepatocellular carcinoma), and she has spearheaded the clinical translation of measles derivatives and their first human testing in patients with ovarian cancer or brain tumors, as well as first human use of live cell carriers for oncolytic virus delivery.
研究兴趣
论文共 476 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
CANCERno. 5 (2024): 750-769
Nature communicationsno. 1 (2024): 493-493
Sani Haider Kizilbash,Kurt A. Jaeckle,Maciej M. Mrugala,Jacob B. Allred,Stephanie L. Safgren, Anita Aracelli Lammers, Wei Zhong,Konstantinos Leventakos,Aaron Scott Mansfield,Mohamed Shanshal,Wen Wee Ma,Joon H. Uhm,
JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023): 3109-3109
引用0浏览0引用
0
0
Evanthia Galanis,Lynn C. Hartmann,William A. Cliby,Harry J. Long,Prema P. Peethambaram, Brigitte A. Barrette,Judith S. Kaur,Paul J. Haluska,Ileana Aderca, Paula J. Zollman,Jeff A. Sloan,Gary Keeney,
crossref(2023)
crossref(2023)
Neuro-Oncologyno. Supplement_5 (2023): v76-v77
引用0浏览0引用
0
0
Neuro-oncologyno. Supplement_5 (2023): v174-v175
引用0浏览0引用
0
0
MOLECULAR THERAPYno. 4 (2023): 156-156
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn