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Our research is focussed on nuclear magnetic resonance (NMR) spectroscopy of membrane proteins. This protein class is essential for signal transduction and the transfer of proteins and small molecules across the biological membrane barrier. The key to understanding these processes is to study these systems in a native environment provided by a phospholipid bilayer. These membrane mimics are being developed and established in the lab and subsequently applied to biologically interesting systems like mitochondrial membrane proteins, G-protein coupled receptors (GPCRs) and their associated G-proteins, which are involved in metabolic diseases, neurological disorders and cancer.
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Journal of Structural Biologyno. 2 (2023): 107970-107970
Nature Structural & Molecular Biologyno. 6 (2023): 761-769
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D-Core
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