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Ph.D., Immunology, Department of Microbiology & Immunology, Northwestern University, U.S.A. 。B. S., Department of Agricultural Chemistry National Taiwan University, Taiwan 。 Chairman & Professor, Institute of Basic Medical Sciences, College of Medicine, Cheng-Kung University, Taiwan (2004-present) 。 Chairman & Professor, Department of Microbiology & Immunology, College of Medicine, Cheng-Kung University, Taiwan (1994-2000) 。 Professor, Department of Microbiology & Immunology, College of Medicine, Cheng-Kung University, Taiwan (1990-present) 。 Associate Professor, Department of Microbiology & Immunology, College of Medicine, Cheng-Kung University, Taiwan (1985-1990) 。 Instructor, Department of Microbiology & Immunology, College of Medicine, Cheng-Kung University, Taiwan (1983-1985)。 RESEARCH INTERESTS Dengue virus infection causes a broad spectrum of disease from mild dengue fever to severe dengue hemorrhagic fever/dengue shock syndrome. Dengue virus infection would also induce autoimmunity. The immunopathogenesis, and the role of antibody-dependent enhancement in dengue virus infection are the aims that we target. SELECTED PUBLICATIONS 1.Lee WC, Lien KY, Lee GB and Lei HY. An integrated microfluidic system using magnetic beads for virus detection. Diag. Micro. Infect. Dis., 60: 51�58, 2008. 2.Huang KJ, Yang YC, Lin YS, Huang JH, Liu HS, Yeh TM, Chen SH, Liu CC and Lei HY. The dual-specific binding of dengue virus and target cells for the antibody-dependent enhancement of dengue virus infection. J. Immunol., 176: 2825-2832, 2006. 3.Hung NT, Lei HY, Lan NR, Lin YS, Huang KJ, Lien LB, Lin CF, Yeh TM, Ha DQ, Huong VTQ, Chen LC, Huang JH, My LT, Liu CC and Halstead SB. Dengue hemorrhagic fever in infants: A study on clinical and cytokine profiles. J. Infect. Dis., 189:221-232, 2004. 4.Liu CC, Huang KJ, Lin YS, Yeh TM, Liu HS and Lei HY. Transient CD4/CD8 ratio inversion and immune deviation during dengue virus infection. J. Med. Virol., 68:241-252, 2002. 5.Lei HY, Yeh TM, Liu HS, Lin YS, Chen SH and Liu CC. Immunopathogenesis of dengue virus infection J. Biomed. Sci., 8:377-388, 2001.