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Our research group use physiological (multiple electrode) tools to explore the computation physiology of the basal ganglia, their disorders and therapy. We record the activity of several neurons in the different basal ganglia nuclei during behavioral tasks and over the wake-sleep cycle. We do it before and after induction of disease-like state (e.g., Parkinson's disease, schizophrenia) in animal models and in human patients undergoing deep brain stimulation (DBS) procedures. Our goal is to provide better understanding of the physiology and pathophysiology of the basal ganglia, and to use this understanding to develop better methods for treatment (eg closed-loop DBS).
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论文共 310 篇作者统计合作学者相似作者
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BRAIN STIMULATIONno. 1 (2024): 125-133
MOVEMENT DISORDERS (2024)
Barbara Hollunder,Jill L. Ostrem, Ilkem Aysu Sahin,Nanditha Rajamani,Simón Oxenford, Konstantin Butenko,Clemens Neudorfer,Pablo Reinhardt, Patricia Zvarova,Mircea Polosan,Harith Akram,Matteo Vissani,
Deep Brain Stimulation (2024)
medRxiv (Cold Spring Harbor Laboratory) (2023)
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Xiaowei Liu, Stefanie Glowinsky,Hodaya Abadi, Juan F León,Wei Wang,David Arkadir,Zvi Israel,Hagai Bergman,Jing Guang
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Movement disorders : official journal of the Movement Disorder Societyno. 6 (2023): 1114-1114
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