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She is a principal investigator of multiple clinical trials focusing on combining novel targeted therapeutics with standard treatment to improve the treatment of both early and late stage breast cancer, and has published widely in this area. Her current research interests include immunotherapy and combinations of targeted agents in the treatment of breast cancer to overcome resistance. She was a member of the steering committee for the EMBRACA and ABRAZO studies that evaluated the efficacy of the PARP inhibitor talazoparib in patients with metastatic breast cancer and germline mutations in BRCA1 and 2. In addition, Dr. Rugo has conducted a number of studies focusing on reducing toxicity from therapy, resulting in approval of scalp cooling to reduce chemotherapy induced hair loss, and a steroid mouthwash to reduce targeted agent stomatitis. She is an investigator and the chair of the Safety Committee for the multicenter adaptively randomized phase II I-SPY2 trial, and serves on the Novel Agents Committee. Dr. Rugo is the co-chair of the Triple Negative Working Group and an active member of the Translational Breast Cancer Research Consortium (TBCRC), and is the principal investigator of several TBCRC trials including a multi-center immunotherapy trial funded by the Breast Cancer Research Foundation (BCRF). She is an active member of the Alliance (formerly CALGB) Breast Committee, as well as ASCO, where she serves on the Guidelines Committee and as an editor for the Education Committee.
In addition to her research, Dr. Rugo is an active clinician, and is committed to education, regularly lecturing locally, nationally and internationally on subjects relating to the treatment of and supportive care for breast cancer. At UCSF, Dr. Rugo runs the Breast Forum, an open bimonthly evening educational session for breast cancer patients, families and friends from throughout the bay area.
Dr. Rugo graduated from the University of Pennsylvania School of Medicine in 1983. She completed a residency in internal medicine and primary care followed by a fellowship in hematology and oncology at the University of California San Francisco. She was a post-doctoral fellow in immunology participating in laboratory research at Stanford University from 1988-1990. In 1990, Dr. Rugo joined the faculty at UCSF in the Division of Hematology and Oncology. Dr. Rugo recognized for her excellence in both patient care and in teaching of both medical students and training physicians. She has received several awards including the Bank of America Gianini Foundation Award and a UCSF Clinical Cancer Center Investigator Research Program intra-mural award. In 2006, she received an honor for her work in Breast Cancer Research by the Friends of the Breast Care Center and received the Cancer Care physician of the year award in 2010 by the Cancer Care National Organization.
In addition to her research, Dr. Rugo is an active clinician, and is committed to education, regularly lecturing locally, nationally and internationally on subjects relating to the treatment of and supportive care for breast cancer. At UCSF, Dr. Rugo runs the Breast Forum, an open bimonthly evening educational session for breast cancer patients, families and friends from throughout the bay area.
Dr. Rugo graduated from the University of Pennsylvania School of Medicine in 1983. She completed a residency in internal medicine and primary care followed by a fellowship in hematology and oncology at the University of California San Francisco. She was a post-doctoral fellow in immunology participating in laboratory research at Stanford University from 1988-1990. In 1990, Dr. Rugo joined the faculty at UCSF in the Division of Hematology and Oncology. Dr. Rugo recognized for her excellence in both patient care and in teaching of both medical students and training physicians. She has received several awards including the Bank of America Gianini Foundation Award and a UCSF Clinical Cancer Center Investigator Research Program intra-mural award. In 2006, she received an honor for her work in Breast Cancer Research by the Friends of the Breast Care Center and received the Cancer Care physician of the year award in 2010 by the Cancer Care National Organization.
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BREAST CANCER RESEARCH AND TREATMENTno. 2 (2024): 197-204
Future oncology (London, England) (2024)
Journal of clinical oncology : official journal of the American Society of Clinical Oncologyno. 9 (2024): 987-993
Denise M. Wolf, Christina Yau,Lajos Pusztai, Rita Nanda,Jo Chien, Erica Stringer-Reasor,Rebecca Shatsky, Claudine Isaacs,MInetta Liu, Hyo Han,Hatem Soliman, Michael Campbell,
Cancer Researchno. 6_Supplement (2024): 1207-1207
Sana Al Sukhun,Sarah Temin,Carlos H Barrios, Nicoleta Zenovia Antone,Yanin Chavarri Guerra,Mariana Chavez Mac Gregor,Rakesh Chopra,Michael A Danso,Henry Leonidas Gomez, N'Da Marcelin Homian,Alaa Kandil,Benda Kithaka,
JCO Global Oncologyno. 10 (2024): e2300285-e2300285
Jordi Rodón,David Demanse,Hope S. Rugo,Howard A. Burris,Rafael Simó,Azeez Farooki,Melissa F. Wellons, Fabrice André,Huilin Hu, Dragica Vuina,Cornelia Quadt,Dejan Juric
Kathy S Albain,Christina Yau,Emanuel F Petricoin,Denise M Wolf,Julie E Lang,A Jo Chien,Tufia Haddad,Andres Forero-Torres,Anne M Wallace,Henry Kaplan, Lajos Pusztai, David Euhus,
Clinical cancer research : an official journal of the American Association for Cancer Researchno. 4 (2024): 729-740
FUTURE ONCOLOGYno. 1 (2024): 5-16
The Lancet Oncologyno. 2 (2024): e73-e83
European Journal of Cancer (2024): 113420-113420
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