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Proper regulation of T-dependent B cell responses is critical for our ability to generate long-term high affinity antibodies (Abs) against multiple pathogens. At the same time, disregulation of B cell responses can lead to development of autoimmunity and cancer. T-dependent immune response is a complex multistep process, where acquisition of antigen and T cell help may lead to B cell activation and differentiation into short-lived antibody-secreting plasma cells (PCs) and/or germinal center (GC) B cells that in turn may give rise to high-affinity long-lived memory B cells and PCs.
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论文共 52 篇作者统计合作学者相似作者
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Fang Ke, Zachary L Benet,Pavel Shelyakin,Olga V Britanova,Neetu Gupta, Alexander L Dent,Bethany B Moore,Irina L Grigorova
Chengyi Li,Ryan Clauson,Luke F Bugada,Fang Ke,Bing He, Zhixin Yu,Hongwei Chen, Binyamin Jacobovitz,Hongxiang Hu, Polina Chuikov,Brett Dallas Hill,Syed M Rizvi,
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ACS NANOno. 13 (2024): 9584-9604
Chengyi Li,Ryan Clauson,Luke F Bugada,Fang Ke,Bing He, Zhixin Yu,Hongwei Chen, Binyamin Jacobovitz,Hongxiang Hu, Polina Chuikov,Brett Dallas Hill,Syed M Rizvi,
ACS nanono. 13 (2024): 9584-9604
International immunology (2023)
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JOURNAL OF IMMUNOLOGYno. 9 (2023): 1298-1307
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