Fundamental processes of life are governed by a number of complicated molecules. The electron microscope, which uses electron beams instead of light, expands the possibilities to image these molecules. However, many biological molecules depend on water, which evaporates in the vacuum of an electron microscope. In the early 1980s Jean Dubochet succeeded in cooling the water so rapidly that it solidified around the molecules without the formation of distorting ice crystals. Electron microscope images provide knowledge that is important for the development of pharmaceuticals, among other things.