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个人简介
His doctoral thesis research was performed in the laboratory of Prof. Michael A. Marletta, one of the key scientists responsible for the discovery of nitric oxide generation by mammalian cells. There, Dr. Stone purified and characterized the sensor for nitric oxide, the soluble form of guanylate cyclase. Using spectral and rapid-kinetic techniques, Dr. Stone discovered that this heme-based sensor has an unusual heme environment, previously unknown in mammalian physiology, which allows the protein to be responsive to physiologic levels of nitric oxide, while not interacting with molecular oxygen.
He also directs the Cardiovascular Histology Core Facility at MGH, which serves as a central core laboratory for NIH-funded multicenter trials relating to cardiovascular diseases.
研究兴趣
论文共 826 篇作者统计合作学者相似作者
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Jana Grune,Geetika Bajpai, Pervin Tülin Ocak,Eva Kaufmann, Kyle Mentkowksi,Steffen Pabel,Nina Kumowski,Fadi E Pulous,Kim A Tran,David Rohde,Shuang Zhang,Yoshiko Iwamoto,
Circulation (2024)
The Lancet Rheumatology (2024)
James R Stone,Vidhya Nair, Gregory A Fishbein, Society for Cardiovascular Pathology Temporal Artery Biopsy Consensus Committee
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology (2024): 107622-107622
Steven Blum,Daniel A. Zlotoff,Neal P. Smith, Isabela J. Kernin,Swetha Ramesh,Giacomo Oliveira,Leyre Zubiri, Joshua Caplin, Nandini Samanta, Sidney Martin, Mike Wang,Alice Tirard,
Cancer Researchno. 6_Supplement (2024): 7474-7474
SCHIZOPHRENIA RESEARCH (2024): 234-236
Journal of clinical pathologyno. 5 (2024): 297-300
Rania Abutarboush,Eileen Reed,Ye Chen,Ming Gu,Cameron Watson, Usmah Kawoos, Jonathan K. Statz,Anna E. Tschiffely, Stephanie Ciarlone, Georgina Perez-Garcia, Miguel A. Gama Sosa, Rita de Gasperi,
JOURNAL OF NEUROTRAUMAno. 5-6 (2024): 685-704
Amr M. Zaki, Sirichai Pasadhika, Jerry C. Huang,Akshay S. Thomas,Bryn M. Burkholder,Lyndell L. Lim, Stephanie M. Llop,Eric B. Suhler,Grazyna Adamus,James T. Rosenbaum
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