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个人简介
Our technology development for OME feeds into several research threads. Our main research interest is in cell division where we study the requirements for segregation of mitotic chromosomes. Our discovery of Bod1, a critical modifier of protein phosphate activity is in mitosis has illuminated the key roles in modulating signalling pathways during chromosomes segregation. Our current focus in collaboration with Angus Lamond’s lab is exploring the role of oxygen-sensing enzymes in assembling components of the mitotic spindle. We also work with the SLS’s National Phenotypic Screening Facility to provide high throughput imaging and large-scale data analytics capabilities for development of new assays, small technologies and analytic tools at the interface of chemistry and biology.
研究兴趣
论文共 202 篇作者统计合作学者相似作者
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LEARNING HEALTH SYSTEMSno. 1 (2024): e10365-e10365
Peter Bajcsy, Sreenivas Bhattiprolu,Katy Boerner,Beth A Cimini,Lucy Collinson,Jan Ellenberg, Reto Fiolka, Maryellen Giger,Wojtek Goscinski,Matthew Hartley,Nathan Hotaling,Rick Horwitz,
arxiv(2024)
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Franz S Gruber, Anthony Richardson,Zoe C Johnston,Rachel Myles,Neil R Norcross,David P Day,Irene Georgiou, Laura Sesma-Sanz,Caroline Wilson,Kevin D Read,Sarah Martins da Silva, Christopher L R Barratt,
PloS oneno. 2 (2024): e0297666-e0297666
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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biorxiv(2023)
Franz S Gruber, Anthony Richardson,Zoe C Johnston,Rachel Myles,Neil R. Norcross,David A. Day,Irene Georgiou, Laura Sesma-Sanz,Caroline Wilson,Kevin D. Read,Sarah Martins da Silva,Christopher L.R. Barratt,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Hao Jiang,Jimena Druker, James W. Wilson,Dalila Bensaddek,Jason R. Swedlow,Sónia Rocha,Angus I. Lamond
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Alexander J. Ropelewski, Megan A. Rizzo,Jason R. Swedlow,Jan Huisken,Pavel Osten,Neda Khanjani,Kurt Weiss,Vesselina Bakalov,Michelle Engle,Lauren Gridley,Michelle Krzyzanowski, Tom Madden,
SCIENTIFIC DATAno. 1 (2022): 449
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