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In clinical digestive diseases, Dr. Horton has an interest in conditions that lead to steatosis and obesity. Currently the laboratory is investigating molecular mediators of steatosis using various mouse models. Investigations from the laboratory have revealed how the primary transcriptional regulators of cholesterol metabolism (sterol regulatory element-binding proteins) are also key regulators of fatty acid synthesis in liver.
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Circulationno. 3 (2024): 171-173
ISCIENCEno. 1 (2024): 108653-108653
Stanislaw Deja,Justin A. Fletcher,Chai-Wan Kim,Blanka Kucejova,Xiaorong Fu, Monika Mizerska, Morgan Villegas,Natalia Pudelko-Malik, Nicholas Browder, Melissa Inigo-Vollmer,Cameron J. Menezes,Prashant Mishra,
Cell Metabolism (2024)
CELL METABOLISMno. 3 (2024): 617-629.e7
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Obesity surgeryno. 8 (2023): 2434-2442
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Diabetesno. Supplement_1 (2022)
P Barton Duell,Francine K Welty,Michael Miller,Alan Chait, Gmerice Hammond,Zahid Ahmad,David E Cohen,Jay D Horton, Gregg S Pressman,Peter P Toth
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