Department of Pharmaceutical Chemistry
University of California San Francisco
I am interested in protein structure and dynamics related to gene expression. We study changes in protein structure that occur on time scales ranging from millions of years to a millionth of a second, with a focus on basic questions of how viruses cross-species and give rise to modern pandemics or how enzyme function is fine-tuned by cellular cues. Research in this area guides development of therapeutics for infectious disease and cancer.