基本信息
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Career Trajectory
Bio
In 1981, Dr Hayes was appointed a Lecturer within the Department of Clinical Chemistry at the University of Edinburgh. Here, he focused research efforts on the biochemistry of the GST superfamily of drug-metabolising enzymes and the induction of certain members by chemoprotective drugs; this led to identification of previously unrecognised inducible GST isoenzymes several of which inactivated the fungal toxin aflatoxin B1. They subsequently demonstrated that upon treatment with chemoprotective agents, induction of these GST could suppress hepatocellular carcinoma caused by exposure to the mycotoxin. In 1991, he took sabbatical leave from the University of Edinburgh to work in the laboratory of Dr Cecil Pickett, Merck Frosst, Montreal, Canada, which was responsible for discovering the antioxidant response element (ARE) in the promoters of genes that can be induced by chemoprotective agents.
Research Interests
Papers共 340 篇Author StatisticsCo-AuthorSimilar Experts
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Redox biology (2024): 103117-103117
Hongyan Wang,Kaihua Liu,Miao Geng, Peng Gao,Xiaoyuan Wu,Yan Hai,Yangxia Li, Yulong Li,Lin Luo,John D. Hayes,Xiu Jun Wang,Xiuwen Tang
crossref(2023)
Hongyan Wang,Kaihua Liu,Miao Geng, Peng Gao,Xiaoyuan Wu,Yan Hai,Yangxia Li, Yulong Li,Lin Luo,John D. Hayes,Xiu Jun Wang,Xiuwen Tang
crossref(2023)
Hongyan Wang,Kaihua Liu,Miao Geng, Peng Gao,Xiaoyuan Wu,Yan Hai,Yangxia Li, Yulong Li,Lin Luo,John D. Hayes,Xiu Jun Wang,Xiuwen Tang
crossref(2023)
Hongyan Wang,Kaihua Liu,Miao Geng, Peng Gao,Xiaoyuan Wu,Yan Hai,Yangxia Li, Yulong Li,Lin Luo,John D. Hayes,Xiu Jun Wang,Xiuwen Tang
crossref(2023)
Hongyan Wang,Kaihua Liu,Miao Geng, Peng Gao,Xiaoyuan Wu,Yan Hai,Yangxia Li, Yulong Li,Lin Luo,John D. Hayes,Xiu Jun Wang,Xiuwen Tang
crossref(2023)
Hongyan Wang,Kaihua Liu,Miao Geng, Peng Gao,Xiaoyuan Wu,Yan Hai,Yangxia Li, Yulong Li,Lin Luo,John D. Hayes,Xiu Jun Wang,Xiuwen Tang
crossref(2023)
Hongyan Wang,Kaihua Liu,Miao Geng, Peng Gao,Xiaoyuan Wu,Yan Hai,Yangxia Li, Yulong Li,Lin Luo,John D. Hayes,Xiu Jun Wang,Xiuwen Tang
crossref(2023)
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Author Statistics
#Papers: 338
#Citation: 41272
H-Index: 87
G-Index: 201
Sociability: 7
Diversity: 0
Activity: 1
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