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个人简介
Jonah is currently the Debbie and Andy Rachleff Distinguished Professor of Neurology. He is a member of the Neuroscience Graduate Program, Vice Chief in the Division of Neuroimmunology and Glial Biology and Co-Director of the Innovation Program for Remyelination and Repair at UCSF.
The Chan laboratory has a long-standing interest in fundamental glial/neuronal interactions and the molecular mechanisms that regulate myelination. Myelination is one of the most exquisite examples of cell-cell interaction found in nature and functions to maximize the efficiency and velocity of action potentials transmitted throughout the nervous system. While much has been learned about the global determinants that generate myelin-forming cells during development, the Chan laboratory is particularly interested in understanding how local environmental cues control the spatiotemporal regulation of differentiation and myelination, including both molecular and biophysical interactions. Identification of an environment that is conducive for myelination could have important implications for efforts aimed at promoting repair and remyelination in the nervous system.
The Chan laboratory has a long-standing interest in fundamental glial/neuronal interactions and the molecular mechanisms that regulate myelination. Myelination is one of the most exquisite examples of cell-cell interaction found in nature and functions to maximize the efficiency and velocity of action potentials transmitted throughout the nervous system. While much has been learned about the global determinants that generate myelin-forming cells during development, the Chan laboratory is particularly interested in understanding how local environmental cues control the spatiotemporal regulation of differentiation and myelination, including both molecular and biophysical interactions. Identification of an environment that is conducive for myelination could have important implications for efforts aimed at promoting repair and remyelination in the nervous system.
研究兴趣
论文共 124 篇作者统计合作学者相似作者
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Thomas O Schrader, Kym I Lorrain, Didier Bagnol, Geraldine C Edu,Alexander Broadhead, Christopher Baccei, Michael M Poon, Karin J Stebbins, Yifeng Xiong, Ariana O Lorenzana,Jonah R Chan,Ari J Green,
ACS chemical neuroscienceno. 3 (2024): 685-698
Elizabeth Odell, Nora Jabassini, Björn Schniedewind,Sarah E. Pease-Raissi,Adam Frymoyer,Uwe Christians,Ari J. Green,Jonah R. Chan,Bridget E.L. Ostrem
bioRxiv the preprint server for biology (2024)
Christian Cordano,Sebastian Werneburg,Ahmed Abdelhak,Daniel Bennett,Alexandra Beaudry-richard,Greg Duncan,Frederike Oertel,John Boscardin,Hao Yiu, Nora Jabassini, Lauren Merritt, Sonia Nocera,
Ahmed Abdelhak,Christian Cordano, Katie Emberley,Greg Duncan, Sonia Nocera, Kirtana Ananth, Nora Jabassini, Kiarra Ning, Henriette Reinsberg,Frederike Oertel,Alexandra Beaudry-Richard,Jens Kuhle,
Neurologyno. 17_supplement_1 (2024)
Proceedings of the National Academy of Sciences of the United States of Americano. 20 (2023)
Sonia Nocera,Jonah R. Chan
Neuronno. 11 (2023): 1689-1691
Alyssa Nylander,Stephanie Hsu,Annika Anderson, Will Rowles,Ann Lazar,Sonia Mayoral,Sarah Pease-Raissi,Chan Jonah,Ari Green,Riley Bove
MULTIPLE SCLEROSIS JOURNAL (2023): 956-956
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Wendy Xin,Megumi Kaneko,Richard H Roth, Albert Zhang, Sonia Nocera,Jun B Ding,Michael P Stryker,Jonah R Chan
bioRxiv : the preprint server for biology (2023)
C. Cordano,E. Caverzasi,N. Papinutto, G. Kirkish, T. Gundel, A. Zhu, A. Akula,W. J. Boscardin, H. Neeb,R. Henry,J. Chan, A. Green
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bioRxiv (Cold Spring Harbor Laboratory)no. 9 (2023): 2180-2195
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