Projects in the Lathia laboratory involve understanding how cancer stem cells interact with their surrounding microenvironment as well as one another with the goal of identifying unique pathways for therapeutic development. Work in the Lathia laboratory has resulted in a Phase 1 clinical trial aimed at targeting myeloid-derived suppressor cells that interact with cancer stem cells to suppress the immune system in glioblastoma.

Dr. Lathia has co-authored over 170 publications and work in his lab is currently supported by multiple National Institutes of Health grants and foundation grants. Dr. Lathia also contributes as a peer reviewer to over 140 journals, serves on the editorial board for Cell Reports, Cancer Research, and Neuro-Oncology, has served on multiple grant review panels for the National Institutes of Health and private foundations. He recently served as a co-editor for a cancer stem cell textbook. Dr. Lathia also serves as a co-organizer for the cancer stem cell meeting held in Cleveland in 2014, 2016, and 2018. At each meeting, the three-day event drew over 300 attendees from over 25 states and 15 countries.