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个人简介
He is Board-certified in Internal Medicine, Hematology and Medical Oncology. He is a past recipient of the American Cancer Society’s Career Development Award, the Leukemia & Lymphoma Society of America’s Fellow and Scholar Awards. He also served as the Eminent Scholar of Georgia Research Alliance, Distinguished Cancer Scientist of Georgia Cancer Coalition and Kansas Bioscience Authority Eminent Scholar. He has been formerly a member of Experimental Therapeutics II and Basic Mechanisms of Cancer Therapy, and Chairperson of the Developmental Therapeutics Study Section. He is the author of more than 220 scholarly articles on cancer research. Dr. Bhalla’s current basic and translational research is supported by multiple NCI RO1 grants of which he is the principal investigator. His research is focused on cancer epigenetics, sigaling and chaperone biology, with the goal to pre-clinically develop novel targeted therapies of leukemia and lymphoma. This research involves elucidating the biology of potential therapeutic targets and mechanisms of activity and resistance to the novel anti-cancer agents that engage the targets and the cancer-specific dependencies. These targets include mutant signaling proteins, molecular chaperones and epigenetic modifiers (writers, eraser and reader proteins). Specifically, the research focus is on mutant NPM1, FLT3 and epigenetic targets such as KDM1A, BET proteins and polycomb complex 2. This research also includes the elucidation of the predictive biomarkers of clinical efficacy of the novel anticancer agents or their combinations.
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