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Research in the Luger Lab focuses on the structural biology of genome organization. We aim to understand the fundamental impact of chromatin architecture on all nuclear processes. We study the interaction of nucleosomes with nuclear factors, as well as structural and mechanistic aspects of the cellular machinery that assembles and disassembles chromatin during transcription, replication, and DNA repair. The evolution of eukaryotic chromatin structure is investigated through structural studies of archaeal and viral chromatin. We use a wide range of approaches ranging from structural biology, biophysics, molecular and cell biology.
研究兴趣
论文共 281 篇作者统计合作学者相似作者
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Nature Structural & Molecular Biologyno. 5 (2023): 568-569
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Antoine Hocher, Shawn P. Laursen,Paul Radford,Jess Tyson,Carey Lambert,Kathryn M. Stevens,Alex Montoya, Pavel V. Shliaha,Mathieu Picardeau,R. Elizabeth Sockett,Karolin Luger,Tobias Warnecke
NATURE MICROBIOLOGYno. 11 (2023): 1-14
Trends in biochemical sciencesno. 4 (2023): 307-310
Timothy Kellett, Rida Noor,Qiong Zhou,Hector Esquer, Rita Sala, Petra Stojanovic,Johannes Rudolph,Karolin Luger,Daniel V. Labarbera
SLAS DISCOVERYno. 8 (2023): 394-401
Biochemistryno. 16 (2023): 2382-2390
biorxiv(2023)
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