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Dr. Katalin Karikó’s research has for decades focused on RNA-mediated mechanisms, with the ultimate goal of developing in vitro-transcribed mRNA for protein therapy. She investigated RNA-mediated immune activation and co-discovered (with Penn Medicine colleague Drew Weissman) that nucleoside modifications suppress the immunogenicity of RNA, which has widened the therapeutic potential of mRNA in treating diseases. This led to the development of the two most effective vaccines for COVID-19, the BioNTech/Pfizer and Moderna vaccines, and holds vast promise for future treatments of many other diseases. Dr. Karikó was recently honored with the Breakthrough Prize in Life Sciences, the Princess of Asturias Award, and the Vilcek Prize for Excellence in Biotechnology. She continues to work on new therapeutic applications of mRNA therapy.
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论文共 104 篇作者统计合作学者相似作者
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Virna Cortez-Retamozo,Donald Shaffer,Katalin Karikó, Marie Bernardo,Timothy R Wagenaar, Hossam Hefesha, Mikhail Levit, Isaac Esparza, Ferdia Bates,Kerstin Andrea Heyl,Christian Hotz
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
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Annals of the New York Academy of Sciencesno. 1 (2023): 65-86
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Ziyin Wang, Egon J. Jacobus, David C. Stirling,Stefanie Krumm,Katie E. Flight, Robert F. Cunliffe, Jonathan Mottl,Charanjit Singh,Lucy G. Mosscrop, Leticia Aragao Santiago,Annette B. Vogel,Katalin Kariko,
MOLECULAR THERAPY NUCLEIC ACIDS (2023): 1-15
Molecular therapy : the journal of the American Society of Gene Therapyno. 5 (2022): 1941-1951
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