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个人简介
Kathryn Lilley's research specialises in the development of cutting edge proteomics technologies. Her research group is exploring ways to:
Define residents of organelles and protein complexes within cells
Use a combination of high throughput mass spectrometry and pattern recognition methods to define genuine residents of complexes and organelles
Monitor concerted changes in location upon cellular perturbation such as drug treatment, mutation etc.
These methods are being used to locate proteins involved in stem cell pluripotency maintenance both in terms of sub cellular location and involvement in multi protein complexes.
She is also interested in what controls the location of proteins in cells and is developing methods to determine the spatial location of translation (where proteins are synthesised).
Define residents of organelles and protein complexes within cells
Use a combination of high throughput mass spectrometry and pattern recognition methods to define genuine residents of complexes and organelles
Monitor concerted changes in location upon cellular perturbation such as drug treatment, mutation etc.
These methods are being used to locate proteins involved in stem cell pluripotency maintenance both in terms of sub cellular location and involvement in multi protein complexes.
She is also interested in what controls the location of proteins in cells and is developing methods to determine the spatial location of translation (where proteins are synthesised).
研究兴趣
论文共 386 篇作者统计合作学者相似作者
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Thomas E. Mulroney,Tuija Pöyry,Juan Carlos Yam-Puc, Maria Rust,Robert F. Harvey,Lajos Kalmar, Emily Horner,Lucy Booth,Alexander P. Ferreira,Mark Stoneley,Ritwick Sawarkar, Alexander J. Mentzer,
Natureno. 7993 (2024): 189-194
Dipan Roy,Poonam Mehra,Vaishnavi Mukkawar,Lisa Clark, Kevin Bellande,Joop EM Vermeer, Raquel Martin Arevallilo,Teva VERNOUX, Kawinnat Sue ob,Andrew R Jones,Ulrike Bechtold,Philip Mark Mullineaux,
biorxiv(2024)
Nature Methodsno. 1 (2024): 60-71
Stephen David Coleman,Lisa Breckels,Ross F Waller,Kathryn S Lilley,Chris Wallace,Paul D.W. Kirk,Oliver M Crook
biorxiv(2024)
Thomas E. Mulroney, Tuija Poyry,Juan Carlos Yam-Puc, Maria Rust, Robert F. Harvey,Lajos Kalmar, Emily Horner,Lucy Booth,Alexander P. Ferreira,Mark Stoneley,Ritwick Sawarkar, Alexander J. Mentzer,
NATUREno. 7993 (2024)
Nature communicationsno. 1 (2023): 4401-16
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Journal of the American Society for Mass Spectrometryno. 7 (2023): 1330-1341
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