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Our research is focused on understanding how neural connections are formed, remodeled, and maintained in the brain and its relevance for cognition and disease. Our work is recognized for (1) uncovering the importance of communication between neurons and astrocytes in the brain, and (2) identifying novel signaling mechanisms underlying synaptic plasticity. In particular, our studies have identified new forms of bidirectional signaling between neurons and astrocytes that regulate both developing and mature synapses and uncovered specific pathways that determine where, when, and how glutamate receptors are produced and regulated to confer synaptic plasticity and learning/memory processes.
Our research is focused on understanding how neural connections are formed, remodeled, and maintained in the brain and its relevance for cognition and disease. Our work is recognized for (1) uncovering the importance of communication between neurons and astrocytes in the brain, and (2) identifying novel signaling mechanisms underlying synaptic plasticity. In particular, our studies have identified new forms of bidirectional signaling between neurons and astrocytes that regulate both developing and mature synapses and uncovered specific pathways that determine where, when, and how glutamate receptors are produced and regulated to confer synaptic plasticity and learning/memory processes.
研究兴趣
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Ya-Ting Chang,Yu-Ju Lee, Minza Haque,Hao-Cheng Chang,Sehrish Javed,Yu Cheng Lin, Yoobin Cho, Joseph Abramovitz, Gabriella Chin, Asma Khamis,Reesha Raja,Keith K. Murai,
JOURNAL OF COMPARATIVE NEUROLOGYno. 1 (2024): e25589-e25589
Journal of neurochemistryno. 1 (2023): 52-75
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Christopher K. Salmon,Tabish A. Syed,J. Benjamin Kacerovsky,Nensi Alivodej,Alexandra L. Schober, Tyler F.W. Sloan,Michael T. Pratte, Michael P. Rosen,Miranda Green, Adario Chirgwin-Dasgupta, Shaurya Mehta, Affan Jilani,
Christopher K Salmon,Gael Quesseveur, Gee Hung Leo Cheong,Sabrina Chierzi, Michael P Rosen,Miranda Green, Andy Y.L. Gao,J. Benjamin Kacerovsky,Keith K Murai
biorxiv(2023)
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Trends in Cell Biology (2023)
Sabrina Chierzi,J Benjamin Kacerovsky, Albert H K Fok,Sylvie Lahaie, Arielle Shibi Rosen,W Todd Farmer,Keith K Murai
FRONTIERS IN CELLULAR NEUROSCIENCE (2021): 702685-702685
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