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In the early 1990s, he led scientists in the identification and analysis of the APC gene, the most frequently mutated tumor suppressor gene in colon cancer. In the mid-1990s, he invented SAGE (Serial Analysis of Gene Expression), allowing the first comprehensive analysis of gene expression in human cancer and leading Kinzler to coin the term “transcriptome,” referring to genes that are transcribed at a particular point in time. In the late 1990s and early 2000s, he invented digital PCR and other digital genomics approaches for the detection of trace levels of tumor DNA. In the late 2000s, Kinzler and Ludwig Center co-director Bert Vogelstein, M.D., led a team of scientists who decoded the genomes of many cancers, including breast, colon, pancreatic, brain, ovarian and liver.
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Journal of computer assisted tomographyno. 6 (2023): 845-849
Proceedings of the National Academy of Sciences of the United States of Americano. 15 (2023): e2220704120-e2220704120
N. Papadopoulos,A.M. Lennon, P. Elias, S. Rego, O. Choudhry, D. Flake,J. Cohen,C. Douville, A. Honushefsky, I. Kinde,A. Klein, Z. Salvati,
Annals of Oncology (2023): S262-S263
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Sumitra Ananda,Yuxuan Wang,Wei Hong,Gary Edward Richardson,Janine Margaret Lombard,Geraldine Goss,Linda R. Mileshkin, Christopher B. Steer, Anne Marie Lennon,Orla McNally, Christopher B. Douville,Maria Popoli,
JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023): 5553-5553
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Abdominal Radiologyno. 2 (2023): 1-11
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