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The objective of our research is to gain insights into the mechanics of cellular processes that impact the genomic structure and the heritance of the genetic material by progenies of proliferating cells. Previously, we have studied mechanisms of DNA rearrangement reactions that impact the stability of the linear organization of the genome. More recently, we have focused our attention to understand the mechanisms of bacterial cellular processes that ensure replicated copies of chromosomes are partitioned into two dividing daughter cells.
Advances of molecular understanding of specific reaction systems we study that are essential for efficient bacterial growth could provide a basis for the future development of novel antibacterial agents to combat disease-causing bacteria.
In a broader sense, progress in these projects is expected to advance our general mechanistic understanding of cellular processes such as biomolecular cargo transport and positioning systems and broad range of meso-scale biological positional control mechanisms that operate at much larger length scale than individual molecular components such as protein molecules that constitute the system.
Advances of molecular understanding of specific reaction systems we study that are essential for efficient bacterial growth could provide a basis for the future development of novel antibacterial agents to combat disease-causing bacteria.
In a broader sense, progress in these projects is expected to advance our general mechanistic understanding of cellular processes such as biomolecular cargo transport and positioning systems and broad range of meso-scale biological positional control mechanisms that operate at much larger length scale than individual molecular components such as protein molecules that constitute the system.
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bioRxiv (Cold Spring Harbor Laboratory) (2021)
user-613ea93be55422cecdace10e(2018)
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The Proceedings of Mechanical Engineering Congress, Japanno. 0 (2018)
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