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Klaus Ley, M.D., and his team study inflammation a defense reaction caused by tissue damage or injury, characterized by redness, heat, swelling, and pain. The primary objective of inflammation is to localize and eradicate the irritant and repair the surrounding tissue. For the survival of the host, inflammation is a necessary and beneficial process. The inflammatory response involves three major stages: first, dilation of capillaries to increase blood flow; second, microvascular structural changes and escape of plasma proteins from the bloodstream; and third, leukocyte transmigration through endothelium and accumulation at the site of injury.
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Circulation researchno. 3 (2022): 258-276
Ryosuke Saigusa, Payel Roy,Antoine Freuchet, Rishab Gulati,Yanal Ghosheh, Sujit Silas Armstrong Suthahar,Christopher P Durant, David B Hanna,William B Kiosses, Marco Orecchioni,Lai Wen,Runpei Wu,
Gregory J Golden,Alejandro Gómez Toledo,Alex Marki,James T Sorrentino,Claire Morris, Raquel J Riley,Charlotte Spliid, Qiongyu Chen,Ingrid Cornax,Nathan E Lewis,Nissi Varki,Dzung Le,
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