基本信息
浏览量:3
职业迁徙
个人简介
Dr. Jacobson's research interests include epidemiologic methods in cohort studies, HIV, effects of therapy on HIV, and infectious causes of cancer, particularly the human herpesvirus-8 (HHV-8) and Kaposi's sarcoma, and the effects of HIV, therapy and age. As the Principal Investigator of the Data and Analytical Coordinating Center for the Multicenter AIDS Cohort Study (MACS), Dr. Jacobson provides epidemiologic expertise in the conduct of the study, with particular attention to the standardization of study protocols and the design of nested studies. Dr. Jacobson chairs the MACS Data Working Group and represents CAMACS in the Malignancy Group of the Clinical Working Group and participates in the MACS Executive Committee. In addition, she provides epidemiologic, methodological and analytic support to the investigators of the Women's Interagency HIV Study (WIHS), and to those involved in the mulicenter cohort study of kidney disease in children (CKID). Dr. Jacobson analyzed the timing of infections with HIV-1 and HHV-8 for progression to Kaposi's sarcoma [J Infect Dis 2000;181:1940-1949]. As an extension of her interest in malignacies and research design, Dr. Jacobson collaborates with investigators from the Department of Environmental Health Sciences in investigations of molecular biomarkers for environmental carcinogens.
Dr. Jacobson is also investigating the use and impact of highly active antiretroviral therapies (HAART), in the context of cohort studies. In one paper, Dr. Jacobson demonstrated the dramatic decline of Kaposi's sarcoma in the HAART era; a similar immediate effect on the incidence of non-Hodgkin's lymphoma was not observed [JAIDS 1999;21:S34-S41]. In another paper, Dr. Jacobson demonstrated that the heterogeneity of using antiretroviral therapies differs according to disease stage [J Clin Epidemiol 2001;54:149-156]. Dr. Jacobson also showed that those starting HAART with <200 cells/µ have the equivalent progression to AIDS as those with approximately 300 more cells in the nautral history era [Am J Epidemiol 2002;155:760-770]. This compliated historical and prospective data provided methods for using biomarker data to established treatment effectiveness. She provides epidemiologic expertise to the analyses of HIV effectiveness, long-term use and outcomes, including behavior related to HAART. Taking advantage of her expertise in epidemiologic methods, Dr. Jacobson instructs doctoral students in the application of these methods in the formation and review of research proposals.
Dr. Jacobson is also investigating the use and impact of highly active antiretroviral therapies (HAART), in the context of cohort studies. In one paper, Dr. Jacobson demonstrated the dramatic decline of Kaposi's sarcoma in the HAART era; a similar immediate effect on the incidence of non-Hodgkin's lymphoma was not observed [JAIDS 1999;21:S34-S41]. In another paper, Dr. Jacobson demonstrated that the heterogeneity of using antiretroviral therapies differs according to disease stage [J Clin Epidemiol 2001;54:149-156]. Dr. Jacobson also showed that those starting HAART with <200 cells/µ have the equivalent progression to AIDS as those with approximately 300 more cells in the nautral history era [Am J Epidemiol 2002;155:760-770]. This compliated historical and prospective data provided methods for using biomarker data to established treatment effectiveness. She provides epidemiologic expertise to the analyses of HIV effectiveness, long-term use and outcomes, including behavior related to HAART. Taking advantage of her expertise in epidemiologic methods, Dr. Jacobson instructs doctoral students in the application of these methods in the formation and review of research proposals.
研究兴趣
论文共 393 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Pediatric Researchpp.1-8, (2024)
Annals of Allergy, Asthma & Immunology (2024)
crossref(2023)
crossref(2023)
Frontiers in pediatrics (2023): 1171214
引用0浏览0WOS引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn