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Luigina Romani is internationally recognized in the area of antifungal immunity — a field in which her major interest is on the comprehension of innate mechanisms of antifungal immunity that lead to the activation of protective and non-protective adaptive immunity. She has been recognized “Fellow" of the American Academy of Microbiology and elected to the American National Academy of Sciences.
She pioneered studies on the role of T cells first (early 80’) and then of the different Th cell subsets (early 90’) in experimental fungal infections. She introduced several novel scientific and translatable concepts which have become popular in the field of medical mycology. Examples are the concept of protective tolerance, the basis of immunotherapy, the use of dendritic cells to develop fungal vaccine, the pathogenetic role of inflammation in infection, the discovery of tryptophan metabolites as potential antifungal strategies and, more recently, the use of functional genomic to predict individual risk for fungal infections in transplanted patients.
She pioneered studies on the role of T cells first (early 80’) and then of the different Th cell subsets (early 90’) in experimental fungal infections. She introduced several novel scientific and translatable concepts which have become popular in the field of medical mycology. Examples are the concept of protective tolerance, the basis of immunotherapy, the use of dendritic cells to develop fungal vaccine, the pathogenetic role of inflammation in infection, the discovery of tryptophan metabolites as potential antifungal strategies and, more recently, the use of functional genomic to predict individual risk for fungal infections in transplanted patients.
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论文共 571 篇作者统计合作学者相似作者
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Pharmaceuticals (Basel, Switzerland)no. 3 (2024): 367
Blood (2024)
Cellsno. 6 (2024)
International Journal of Molecular Sciencesno. 19 (2023): 14868-14868
Scientific reportsno. 1 (2023): 22692-22692
PNAS nexusno. 3 (2023)
C. Costantini, G. Pampalone,M. Pariano, T. Zelante,L. Macchioni,R. Galarini,E. Camaioni, F. Paoletti, F. Catalano, M. Davidescu,C. Stincardini,M. Bellet,
Journal of Cystic Fibrosis (2023): S78-S79
Nature communicationsno. 1 (2023): 5753-21
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