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Our laboratory studies cancer cell metabolism, tumor immunology, metastasis, and responses to oxygen/nutrient deprivation in the tumor microenvironment.
Key words: hypoxia; cancer metabolism; immunology; metastasis; in vivo and ex vivo models of pancreatic, liver, and renal cancer, and sarcoma.
Research Techniques:
Generation of genetically engineered and patient derived xenotransplanted mice, CRISPR-based gene editing and genome-wide screens, ex vivo 3D organotypic culture, integrated “omics” characterization of human tumors, TCGA data mining, bioinformatics, next generation sequencing, ChIP-Seq, epigenetics, proteomics, array cGH (the Illumina SNP platform), molecular biology, biochemistry, metabolomics, NMR spectroscopy, mass spectrometry, histology, immunohistochemistry, multiplexed immunofluorescence, animal s
Our laboratory studies cancer cell metabolism, tumor immunology, metastasis, and responses to oxygen/nutrient deprivation in the tumor microenvironment.
Key words: hypoxia; cancer metabolism; immunology; metastasis; in vivo and ex vivo models of pancreatic, liver, and renal cancer, and sarcoma.
Research Techniques:
Generation of genetically engineered and patient derived xenotransplanted mice, CRISPR-based gene editing and genome-wide screens, ex vivo 3D organotypic culture, integrated “omics” characterization of human tumors, TCGA data mining, bioinformatics, next generation sequencing, ChIP-Seq, epigenetics, proteomics, array cGH (the Illumina SNP platform), molecular biology, biochemistry, metabolomics, NMR spectroscopy, mass spectrometry, histology, immunohistochemistry, multiplexed immunofluorescence, animal s
研究兴趣
论文共 492 篇作者统计合作学者相似作者
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CANCER RESEARCHno. 7 (2024): 977-993
Oncotarget (2024): 123-123
Nature Reviews Nephrologyno. 4 (2024): 233-250
Brooke A Brown,Paul J Myers,Sara J Adair,Jason R Pitarresi,Shiv K Sah-Teli, Logan A Campbell, William S Hart, Michelle C Barbeau, Kelsey Leong, Nicholas Seyler,William Kane,Kyoung Eun Lee,
Cancer research (2024)
COLD SPRING HARBOR PERSPECTIVES IN MEDICINEno. 2 (2024)
Pengfei Yu, Shuwen Cao,Shyh-Ming Yang,Ganesha Rai,Natalia J Martinez,Adam Yasgar,Alexey V Zakharov,Anton Simeonov, William A Molina Arocho, Graham P Lobel,Hesham Mohei, Alexis L Scott,
Cancer immunology researchno. 2 (2024): 180-194
Fuming Li,Pingyu Liu, Wen Mi,Liucheng Li,Nicole M. Anderson,Nicholas P. Lesner,Michelle Burrows,Jacqueline Plesset, Ariana Majer, Guanlin Wang,Jinyang Li, Lingzhi Zhu,
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