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个人简介
During his postdoctoral training at Stanford under the mentorship of Howard Chang and Thomas Montine, he focused on dissecting epigenomic dysregulation in cancer and neurodegenerative disease. His work has generated atlases of the epigenomes of leukemia cells and brain cells, and paves the way to identify novel therapeutic interventions that target the intersection of genetic and epigenetic determinants of disease. His presentations have been prized at many symposiums, and he is the recipient of many awards and fellowships, most recently a K99 award from the NIH and a Scholars Award from the American Society of Hematology.
Ryan Corces studies the contributions of genetic and non-genetic factors to neurodegenerative diseases. While genetic mutations modify genes directly, non-genetic factors, such as previous illnesses, exposure to environmental chemicals, or aging, can leave lasting imprints on the epigenome, the DNA sequences and associated proteins that control gene activation. Using computational biology, large-scale screens, and single-cell technologies, Corces probes the epigenome of cells derived from patients, with the aim to understand how it impacts disease risk and to develop novel avenues for therapeutic interventions.
Ryan Corces studies the contributions of genetic and non-genetic factors to neurodegenerative diseases. While genetic mutations modify genes directly, non-genetic factors, such as previous illnesses, exposure to environmental chemicals, or aging, can leave lasting imprints on the epigenome, the DNA sequences and associated proteins that control gene activation. Using computational biology, large-scale screens, and single-cell technologies, Corces probes the epigenome of cells derived from patients, with the aim to understand how it impacts disease risk and to develop novel avenues for therapeutic interventions.
研究兴趣
论文共 77 篇作者统计合作学者相似作者
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bioRxiv : the preprint server for biology (2024)
Michael R. McKeown,M. Ryan Corces,Matthew L. Eaton,Chris Fiore,Emily Lee, Jeremy T. Lopez,Mei Wei Chen,Darren Smith,Steven M. Chan, Julie L. Koenig, Kathryn Austgen,Matthew G. Guenther,
crossref(2023)
Florian V. De Rop,Gert Hulselmans, Chris Flerin,Paula Soler-Vila, Albert Rafels,Valerie Christiaens,Carmen Bravo González-Blas, Domenica Marchese, Ginevra Caratù,Suresh Poovathingal,Orit Rozenblatt-Rosen, Michael Slyper,
Eloise Berson, Anjali Sreenivas,Thanaphong Phongpreecha,Amalia Perna,Fiorella C. Grandi, Lei Xue,Neal G. Ravindra, Neelufar Payrovnaziri,Samson Mataraso,Yeasul Kim,Camilo Espinosa,Alan L. Chang,
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Matvei S Khoroshkin, Andrey Buyan,Martin Dodel,Albertas Navickas,Johnny Yu, Fathima Trejo, Anthony Doty, Rithvik Baratam,Shaopu Zhou,Tanvi Joshi,Sohit Miglani,Benedict Choi,
biorxiv(2023)
Tomasz Wlodarczyk,Aaron Lun, Diana Wu, Shreya Menon,Shushan Toneyan,Kerstin Seidel,Liang Wang,Jenille Tan, Shang-Yang Chen, Timothy Keyes, Aleksander Chlebowski,Yu Guo,
biorxiv(2023)
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Kevin A Nuno,Armon Azizi,Thomas Köhnke,Caleb A Lareau, Asiri Ediwirickrema,M Ryan Corces,Ansuman T Satpathy,Ravindra Majeti
bioRxiv : the preprint server for biology (2023)
Michael R. McKeown,M. Ryan Corces,Matthew L. Eaton, Chris Fiore,Emily Lee,Jeremy T. Lopez,Mei Wei Chen,Darren Smith,Steven M. Chan,Julie L. Koenig, Kathryn Austgen,Matthew G. Guenther,
crossref(2023)
biorxiv(2022)
Blood Cancer Discoveryno. 4 (2022): 346-367
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