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The guiding principle of this research is that by comparing the signaling molecules that operate in these two processes we can determine whether there are any fundamental differences (is regeneration a process of re-development?) and whether we can induce regeneration by re-awakening developmental pathways. Much of this work is centered on one signaling pathway, that of retinoic acid and the organisms used range from axolotls (the champion of regeneration) to mice. Most recently we have discovered that the spiny mouse can regenerate its skin wounds perfectly by replacing hairs, sebaceous glands, dermis, smooth muscle and skeletal muscle and much of our work is now concerned with what seems to be a remarkable regenerating mammal.
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论文共 304 篇作者统计合作学者相似作者
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Animalsno. 1 (2024): 64
GENESno. 3 (2024): 310
WOUND REPAIR AND REGENERATIONno. 2 (2023): S13-S13
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iScienceno. 6 (2023): 106779-106779
Osteoarthritis and Cartilage (2023): S307-S308
SSRN Electronic Journal (2022)
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