For the past few years, Santello has been working on the control of the hand as this system is characterized by a large number of elements or degrees of freedom (i.e., muscles, joints). Hence, the hand's motor system is particularly useful to address questions related to neural strategies and mechanisms underlying the control of complex movements, i.e., coordination of hand muscles, motion and forces of multiple digits. Current work in the Neural Control of Movement Laboratory focuses on basic and applied motor control problems including (a) control of kinematics, kinetics and EMG of hand muscles during object grasping and manipulation, (b) investigation of electrical stimulation for sensory substitution/rehabilitation, (c) mathematical modeling of motor unit behavior, and (d) assessment of effects of musculoskeletal and neurological diseases on hand control finalized to the development of sensorimotor rehabilitation intervention.