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个人简介
Research Interests
Dr. Schiffman has studied human papillomavirus (HPV) and cervical cancer for more than 35 years. He has conducted and collaborated on many large molecular epidemiologic observational studies and a few major trials Through a natural progression of studies, he has pursued three main scientific themes: 1) HPV Natural History and Cervical Carcinogenesis; 2) Translational Studies of HPV Testing, Cytology, Colposcopy, and Vaccines; and 3) Risk Prediction and Cervical Cancer Prevention.
With regard to natural history, he has investigated HPV at the level of individual infections, women’s experience with HPV during their lifetimes, and populations. His work has helped promulgate a multi-stage causal model of HPV and cervical carcinogenesis based on a few distinct steps: acute infection with carcinogenic HPV type(s), detectable viral persistence (rather than clearance) linked to development of cervical precancer (CIN3/AIS and invasion). The natural history studies gave rise to translational research on HPV tests, serology, cytology, colposcopy, histology, and vaccines. He has helped to show that HPV testing is useful along the entire course of cervical cancer prevention, and must be integrated now with HPV vaccination. With Dr. Nicolas Wentzensen, he is the Principal Investigator of the Cancer Cures “Moonshot” Initiative called “Accelerated Control of Cervical Cancer.”
研究兴趣
论文共 673 篇作者统计合作学者相似作者
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Journal of lower genital tract diseaseno. 1 (2024): 3-6
Aimee J. Koestler,Chase W. Nelson,Meredith Yeager,Zigui Chen,Laurie Burdett, Sambit K. Mishra,Michael Dean,Elizabeth Suh-Burgmann,Thomas Lorey, Phillip E. Castle,Mark Schiffman,Lisa Mirabello
Cancer Researchno. 6_Supplement (2024): 3948-3948
Chemtai Mungo, Anagha Guliam,Lameck Chinula,Federica Inturrisi, Lizzie Msowoya, Tawonga Mkochi, Siniya Jawadu, Silvia de Sanjosé,Mark Schiffman,Jennifer H Tang,Jennifer S Smith
medRxiv : the preprint server for health sciences (2024)
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTEno. 1 (2024): 26-33
Federica Inturrisi,Silvia de Sanjose,Kanan T. Desai,Casey Dagnall,Didem Egemen,Brian Befano,Ana Cecilia Rodriguez,Jose A. Jeronimo,Rosemary E. Zuna, Amanda Hoffman, Sepideh Farhat Nozzari,Joan L. Walker,
ELIFE (2024)
Kanan T. Desai, Natasha Hansen, Ana -Cecilia Rodriguez,Brian Befano,Didem Egemen,Julia C. Gage,Nicolas Wentzensen, Catya Lopez,Jose Jeronimo, Silvia de Sanjose,Mark Schiffman
crossref(2023)
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