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Our current understanding of T-cell mediated immunity has been established through the intense study of “conventional” αβ T-cells and the αβ T-cell receptor’s (TCR) remarkable ability to detect pathogen infected cells by recognising foreign peptide antigens presented by major histocompatibility complexes (MHCs). Despite human γδ T-cells being implicated in immunity to infectious diseases, the role of human γδ T-cells and the mechanisms they use to detect infection are largely unclear. γδ T-cells are defined as an innate-like T-cell population, operating outside of peptide/MHC recognition, comprising restricted γδTCR chain usage from birth and rapidly responding to TCR independent stimuli.
Research Interests
Papers共 42 篇Author StatisticsCo-AuthorSimilar Experts
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A. Das, G. Ariyakumar, N. Gupta, S. Kamdar, A. Barugahare, D. Deveson-Lucas, S. Gee,K. Costeloe,M. S. Davey,P. Fleming,D. L. Gibbons
Nature Communicationsno. 1 (2024)
IMMUNOLOGY AND CELL BIOLOGYno. 4 (2023): 321-332
Jack L. McMurray,Anouk von Borstel,Taher E. Taher,Eleni Syrimi,Graham S. Taylor,Maria Sharif,Jamie Rossjohn,Ester B.M. Remmerswaal,Frederike J. Bemelman,Felipe A. Vieira Braga,Xi Chen,Sarah A. Teichmann,Fiyaz Mohammed,Andrea A. Berry,Kirsten E. Lyke,Kim C. Williamson,Michael J.T. Stubbington,Martin S. Davey,Carrie R. Willcox,Benjamin E. Willcox
Research Square (Research Square) (2022)
Biochemical Society transactionsno. 5 (2021): 1985-1995
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Author Statistics
#Papers: 44
#Citation: 1949
H-Index: 23
G-Index: 34
Sociability: 6
Diversity: 3
Activity: 21
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