基本信息
浏览量:228
职业迁徙
个人简介
The overarching goal of Dr. Kretzler's research is to define chronic kidney disease in mechanistic terms and use this knowledge for targeted therapeutic interventions. To reach this goal he and his team have developed a translational research pipeline centered on integrated systems biology analysis of renal disease.
Dr. Kretzler has 25 years of experience on interdisciplinary data integration of large-scale data sets in international multi-disciplinary research networks in the United States, Europe, China, and sub-Saharan Africa. These studies enable precision medicine across the genotype-phenotype continuum using carefully monitored environmental exposures, genetic predispositions, transcriptional networks, proteomic profiles, metabolic fingerprints, digital histological biopsy archive and prospective clinical disease characterization. The molecular mechanisms identified have resulted in new disease predictors, new drug development and successful clinical trials of novel therapeutic modalities in chronic kidney disease.
Dr. Kretzler has 25 years of experience on interdisciplinary data integration of large-scale data sets in international multi-disciplinary research networks in the United States, Europe, China, and sub-Saharan Africa. These studies enable precision medicine across the genotype-phenotype continuum using carefully monitored environmental exposures, genetic predispositions, transcriptional networks, proteomic profiles, metabolic fingerprints, digital histological biopsy archive and prospective clinical disease characterization. The molecular mechanisms identified have resulted in new disease predictors, new drug development and successful clinical trials of novel therapeutic modalities in chronic kidney disease.
研究兴趣
论文共 599 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Viji Nair,Jennifer L. Harder,Jamal El Saghir,Felix H. Eichinger,Helen Looker, Shannon M. Harlan,Hana Baker, Frank C. Brosius,Kevin L. Duffin,Robert G. Nelson,Matthias Kretzler,Wenjun Ju
Kidney International Reportsno. 4 (2024): S230
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGYno. 1 (2024): F30-F38
KIDNEY INTERNATIONALno. 2 (2024): 242-244
Kidney internationalno. 3 (2024): 639-639
Debora L. Gisch,Michelle Brennan,Blue B. Lake, Jeannine Basta, Mark S. Keller,Ricardo Melo Ferreira,Shreeram Akilesh,Reetika Ghag,Charles Lu,Ying-Hua Cheng,Kimberly S. Collins,Samir V. Parikh,
Nature Communicationsno. 1 (2024): 1-21
Camille Cohen, Rana Mhaidly, Hugo Croizer,Yann Kieffer,Renaud Leclere,Anne Vincent-Salomon, Catherine Robley,Dany Anglicheau,Marion Rabant,Aurélie Sannier,Marc-Olivier Timsit,Sean Eddy,
Nature Communicationsno. 1 (2024): 1-23
Pediatric nephrology (Berlin, Germany)pp.1-14, (2024)
Julio Saez-Rodriguez, Jon Barratt,Haresh Selvaskandan,Raphael Duivenvoorden,Matthias Kretzler, Laura Mariani,Celine Berthier, Anna Witsap,Hannes Olauson,Annika Wernerson,Loreto Gesualdo,Jenny Nyström
Kidney International Reportsno. 4 (2024): S177-S178
Kidney International Reportsno. 4 (2024): S510-S511
Alice Horisberger,Alec Griffith,Joshua Keegan,Arnon Arazi, John Pulford, Ekaterina Murzin,Kaitlyn Howard,Brandon Hancock,Andrea Fava,Takanori Sasaki,Tusharkanti Ghosh,Jun Inamo,
biorxiv(2024)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn