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Dr. Donnenberg’s active research effort is focused on the molecular pathogenesis of enteric infections, particularly those due to enteropathogenic Escherichia coli and Clostridium difficile. Despite the vast evolutionary distance separating these potentially deadly microbes, they both produce similar surface appendages called type IV pili. Such pili are used by numerous pathogens to colonize and move along host cell surfaces. Pilus assembly and retraction are powered by a multicomponent membrane-spanning molecular machine. Understanding how this machine works is a long-term goal of the lab. His work has been continuously funded by the NIH for 25 years. His publications include over 100 original manuscripts, numerous reviews, books and book chapters, with over 15,000 citations (view his NCBI library). He is a Fellow of the Infectious Diseases Society of America and the American Academy of Microbiology and a member of the American Society for Clinical Investigation. He is a recipient of the Oswald Avery Award from the Infectious Diseases Society of America.
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论文共 196 篇作者统计合作学者相似作者
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EcoSal Pluspp.eesp00032023-eesp00032023, (2024)
Journal of Biological Chemistryno. 3 (2024)
bioRxiv (Cold Spring Harbor Laboratory) (2020)
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