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The Mak Research Lab is focused on multiscale mechanobiology in cancer and development. We develop interdisciplinary approaches, integrating microfluidics, computational modeling, and novel experimental systems, to decipher the principles driving emergent mechanobiological phenomena from the molecular to multicellular scales, including structure formation and functionality of cytoskeletal networks, invasive behavior of tumor cells, and collective dynamics of tumors, organoids, and tissues. We aim to bridge the gap between molecular signatures and mechanical phenotypes, especially in cancer metastasis and tissue morphogenesis.
The Mak Research Lab is focused on multiscale mechanobiology in cancer and development. We develop interdisciplinary approaches, integrating microfluidics, computational modeling, and novel experimental systems, to decipher the principles driving emergent mechanobiological phenomena from the molecular to multicellular scales, including structure formation and functionality of cytoskeletal networks, invasive behavior of tumor cells, and collective dynamics of tumors, organoids, and tissues. We aim to bridge the gap between molecular signatures and mechanical phenotypes, especially in cancer metastasis and tissue morphogenesis.
研究兴趣
论文共 57 篇作者统计合作学者相似作者
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Journal of Nanobiotechnologyno. 1 (2023): 457-457
David Boehringer,Andreas Bauer, Ivana Moravec, Lars Bischof,Delf Kah,Christoph Mark,Thomas J. Grundy, Ekkehard Goerlach, Geraldine M. O'Neill,Silvia Budday,Pamela L. Strissel,Reiner Strick,
MATRIX BIOLOGY (2023): 39-48
bioRxiv : the preprint server for biology (2023)
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Xiangyu Gong,Zhang Wen, Zixie Liang,Hugh Xiao,Sein Lee, Thomas Wright,Ryan Y Nguyen, Alejandro Rossello,Michael Mak
bioRxiv : the preprint server for biology (2023)
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Ryan Y Nguyen,Aidan T Cabral, Alejandro Rossello-Martinez,Alessandro Zulli,Xiangyu Gong,Qiuting Zhang,Jing Yan,Michael Mak
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Xingjian Zhang, Xin Shi,Dingyao Zhang,Xiangyu Gong,Zhang Wen,Israel Demandel, Junqi Zhang, Alejandro Rossello -Martinez,Trevor J. Chan,Michael Mak
bioRxiv : the preprint server for biology (2023)
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