His area of expertise includes Organic Chemistry, Active Metals in Synthesis, Organic Synthesis, Organolithium Compounds, Asymmetric Catalysis, Organomagnesium Compounds, Nanoparticles in Synthesis, and Organozinc Compounds.

He is a co-author of more than 400 papers mainly in the field of the development of new Methodologies Involving Organometallic Intermediates, and three patents. He is member of advisory board in Tetrahedron, Tetrahedron Letters, Chemistry Letters, and European Journal of Organic Chemistry, Trends in Organic Chemistry, Current Organic Chemistry and Current Chemical Biology, being Past Regional Editor of Letters in Organic Chemistry. He has supervised 45 PhD students. Dr. Miguel received honors include Japan Society for the Promotion of Science Prize, the French-Spanish Prize of the Societe Francaise de Chimie, the CA Stiefvater Memorial Lecture Award, the Nagase Science and Technology Foundation fellowship, the Cellchem Lectureship, the Singenta Lectureship and the Fundeun-Iberdrola Prize. His current research interest is focused on the preparation of very reactive Functionalized Organometallic Compounds and their use in Synthetic Organic Chemistry, Arene-Catalyzed Activation of different metals, preparation of new Metal-Based Catalysts, Treats including Metallic Nanoparticles, for Homogeneous and Heterogeneous reactions and selective Asymmetric Catalysis.