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The Danial Lab focuses on molecular mechanisms and biologic consequences of cellular fuel choices. Different cell states have distinct anabolic and catabolic needs that are fulfilled by processing specific metabolic substrates. As such, cells’ fuel choice can influence transitions in and out of quiescence, resistance/sensitivity to oxidative stress, metabolic adaptations to nutrient changes, and cell identity, including epigenetic regulation. Understanding how these fuel preferences are controlled and defining their specific metabolic outputs will provide a molecular handle on modulating cell behavior in normal physiology and in pathologic conditions.
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论文共 86 篇作者统计合作学者相似作者
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Sina Neyazi,Pruthvi S. Gowda,Maria Trissal,Jay-Miguel Fonticella,Erika P. Portero, John-Paul Haley-Read, Emily P. Anderson,Nika N. Danial,Mariella G. Filbin
Neuro-Oncologyno. Supplement_1 (2023): i19-i19
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Jennifer Ngo,Dong Wook Choi,Illana A Stanley,Linsey Stiles,Anthony J A Molina,Pei-Hsuan Chen,Ana Lako, Isabelle Chiao Han Sung,Rishov Goswami, Min-Young Kim,Nathanael Miller,Siyouneh Baghdasarian,
The EMBO journalno. 11 (2023): e111901-e111901
Ketogenic Diet and Metabolic Therapiespp.321-335, (2022)
Science Advancesno. 39 (2022): eabq0117-eabq0117
semanticscholar(2022)
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James A. Olzmann,Sarah-Maria Fendt,Yatrik M. Shah,Karen Vousden,Navdeep Chandel, Tiffany Horng,Nika Danial,Benjamin Tu,Heather Christofk,Matthew G. Vander Heiden,Kathryn Wellen
Molecular Cellno. 18 (2021): 3659-3664
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