Oliver Stegle

Department Empirical Inference|Max Planck Institute for Biological Cybernetics|Max Planck Institute for Developmental Biology

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Papers137 papers

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Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation

J Jerber,DD Seaton, ASE Cuomo, N Kumasaka, J Haldane, J Steer, M Patel, D Pearce, M Andersson,MJ Bonder, E Mountjoy, M Ghoussaini

Nature genetics, pp.1-29, (2021)

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Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats

David Jakubosky,Erin N Smith,Matteo D'Antonio,Marc Jan Bonder, William W Young Greenwald, Agnieszka D'Antonio-Chronowska,Hiroko Matsui,Oliver Stegle,Stephen B Montgomery,Christopher DeBoever,Kelly A Frazer

NATURE COMMUNICATIONS, no. 1 (2020): 2928-15

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Genetic Analyses of Blood Cell Structure for Biological and Pharmacological Inference

Parsa Akbari, Dragana Vuckovic, Tao Jiang, Kousik Kundu, Roman Kreuzhuber, Erik L Bao, Louisa Mayer, Janine H Collins,Kate Downes, Michel Georges,Luigi Grassi, Jose A Guerrero

bioRxiv, pp.1-21, (2020)

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Using the past to estimate sensory uncertainty

Ulrik Beierholm,Tim Rohe, Ambra Ferrari,Oliver Stegle,Uta Noppeney

eLife, (2020)

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Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

Anna S E Cuomo,Daniel D Seaton,Davis J McCarthy, Iker Martinez,Marc Jan Bonder, Jose Garcia-Bernardo, Shradha Amatya,Pedro Madrigal, Abigail Isaacson,Florian Buettner,Andrew Knights,Kedar Nath Natarajan

NATURE COMMUNICATIONS, no. 1 (2020): 810-14

Cited by13WOSBibtex

Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

Christian H Holland, Jovan Tanevski, Javier Perales-Patón, Jan Gleixner, Manu P Kumar,Elisabetta Mereu, Brian A Joughin,Oliver Stegle,Douglas A Lauffenburger,Holger Heyn, Bence Szalai,Julio Saez-Rodriguez

Genome Biology, no. 1 (2020): 1-19

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Genetic associations at regulatory phenotypes improve fine-mapping of causal variants for twelve immune-mediated diseases

Kousik Kundu, Alice L. Mann, Manuel Tardaguila,Stephen Watt,Hannes Ponstingl, Louella Vasquez,Nicholas W. Morrell,Oliver Stegle,Tomi Pastinen,Stephen J. Sawcer,Carl A. Anderson,Klaudia Walter

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The single-cell eQTLGen consortium

Monique Gp van der Wijst, Dylan H de Vries,Hilde E Groot,Gosia Trynka, Chung-Chau Hon,Marc-Jan Bonder,Oliver Stegle, Martijn Nawijn, Youssef Idaghdour,Pim van der Harst, Chun J Ye,Joseph Powell

ELIFE, (2020)

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Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes

Davis J McCarthy,Raghd Rostom, Yuanhua Huang, Daniel J Kunz,Petr Danecek,Marc Jan Bonder, Tzachi Hagai, Ruqian Lyu,Wenyi Wang,Daniel J Gaffney,Benjamin D Simons,Oliver Stegle

NATURE METHODS, no. 4.0 (2020): 414.0-+

Cited by3WOSBibtex

Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation

Daniel Ortmann, Stephanie Brown,Anne Czechanski, Selcan Aydin,Daniele Muraro, Yuanhua Huang, Rute A Tomaz,Anna Osnato, Giovanni Canu, Brandon T Wesley, Daniel A Skelly,Oliver Stegle

CELL STEM CELL, no. 3 (2020): 470.0-+

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Effects of the COVID-19 pandemic on life scientists

Jan O. Korbel,Oliver Stegle

Genome Biology, no. 1 (2020): 1-5

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Population-scale proteome variation in human induced pluripotent stem cells

Bogdan Andrei Mirauta,Daniel D Seaton,Dalila Bensaddek,Alejandro Brenes Murillo,Marc Jan Bonder, Helena Kilpinen,Oliver Stegle,Angus I Lamond

ELIFE, (2020)

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MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data

Ricard Argelaguet, Damien Arnol, Danila Bredikhin, Yonatan Deloro, Britta Velten,John C Marioni,Oliver Stegle

Genome Biology, no. 1 (2020): 1-17

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A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, Fátima Santos, Oana Kubinyecz, Mélanie A Eckersley-Maslin,Oliver Stegle,Wolf Reik

CELL SYSTEMS, no. 1 (2020): 25-+

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Properties of structural variants and short tandem repeats associated with gene expression and complex traits

David Jakubosky,Matteo D'Antonio,Marc Jan Bonder, Craig Smail, Margaret K R Donovan, William W Young Greenwald,Hiroko Matsui, Agnieszka D'Antonio-Chronowska,Oliver Stegle,Erin N Smith,Stephen B Montgomery,Christopher DeBoever

NATURE COMMUNICATIONS, no. 1 (2020): 2927-15

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Publisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

NATURE COMMUNICATIONS, no. 1 (2020): 1572

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Multi-omics profiling of mouse gastrulation at single-cell resolution

Argelaguet,Ricard,Stegle,Oliver,Marioni,John C.,Ibarra-Soria,Ximena,Buettner,Florian,Krueger,Felix,Dean,Wendy,Reik,Wolf,Clark,Stephen J.,Mohammed,Hisham, Stapel,L. Carine,Krueger,Christel

Nature, (2019)

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DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development

Judith Kraiczy,Komal M Nayak,Kate J Howell,Alexander Ross,Jessica Forbester, Camilla Salvestrini, Roxana Mustata, Sally Perkins,Amanda Andersson-Rolf, Esther Leenen, Anke Liebert,Ludovic Vallier

GUT, no. 1.0 (2019): 49-61

Cited by45WOSBibtex

Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

Stephanie M Linker, Lara Urban,Stephen J Clark, Mariya Chhatriwala, Shradha Amatya,Davis J McCarthy,Ingo Ebersberger,Ludovic Vallier,Wolf Reik,Oliver Stegle,Marc Jan Bonder

Genome biology, no. 1 (2019): 30

Cited by17WOSBibtex

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors

Alessandra Vigilante, Anna Laddach, Nathalie Moens, Ruta Meleckyte,Andreas Leha, Arsham Ghahramani, Oliver J Culley, Annie Kathuria, Chloe Hurling, Alice Vickers, Erika Wiseman, Mukul Tewary

Cell Reports, no. 8 (2019): 2078-2087.e3

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Oliver StegleBinding

Papers137 papers

Oliver Stegle