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Structural and biophysical studies of Botulinum neurotoxins and novel Cancer targets in nucleotide metabolism
- The botulinum neurotoxins
The botulinum neurotoxins are the most toxic substances known; they are one million times more toxic than the cobra toxin. In spite of their extreme toxicity there has been a rapid expansion of the medical applications for the botulinum neurotoxins, with new applications constantly being discovered. This line of treatment is becoming the standard procedure for many conditions. The toxins are possible agents for bioterrorism and the development of countermeasures and vaccines are of high priority. We are studying the toxins using a wide variety of methods, including X-ray crystallography, to understand toxins basic mechanism and to improve their therapeutic properties.
Structural and biophysical studies of Botulinum neurotoxins and novel Cancer targets in nucleotide metabolism
- The botulinum neurotoxins
The botulinum neurotoxins are the most toxic substances known; they are one million times more toxic than the cobra toxin. In spite of their extreme toxicity there has been a rapid expansion of the medical applications for the botulinum neurotoxins, with new applications constantly being discovered. This line of treatment is becoming the standard procedure for many conditions. The toxins are possible agents for bioterrorism and the development of countermeasures and vaccines are of high priority. We are studying the toxins using a wide variety of methods, including X-ray crystallography, to understand toxins basic mechanism and to improve their therapeutic properties.
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论文共 154 篇作者统计合作学者相似作者
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Toxicon (2024): 107452
FEBS JOURNALno. 4 (2024): 676-689
Julia Kinsolving,Julien Bous,Pawel Kozielewicz,Sara Kosenina,Rawan Shekhani,Lukas Gratz,Geoffrey Masuyer, Yuankai Wang,Pal Stenmark,Min Dong,Gunnar Schulte
CELL REPORTSno. 2 (2024): 113727-113727
Robert Gustafsson,Ann-Sofie Jemth,Nina M.S. Gustafsson,Katarina Färnegårdh,Olga Loseva,Elisée Wiita, Nadilly Bonagas,Leif Dahllund,Sabin Llona-Minguez,Maria Häggblad,Martin Henriksson, Yasmin Andersson,
crossref(2023)
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Lars Bräutigam,Linda Pudelko,Ann-Sofie Jemth,Helge Gad, Mohit Narwal,Robert Gustafsson,Stella Karsten, Jordi Carreras Puigvert,Evert Homan,Carsten Berndt,Ulrika Warpman Berglund,Pål Stenmark,
crossref(2023)
ChemMedChemno. 1 (2023)
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